Pirafene 2mg/5ml Syrup

Chlorpheniramine Maleate
2mg/5ml
THE MEMPHIS CHEMICAL CO.
Pack size 120ml Bottle
Dispensing mode POM
Source EGYPT
AgentModern Pharmaceutical Co.
Retail Price 5.00 AED

Available as:

4mg - Tablets

Pirafene 2mg/5ml Overview

Pirafene 2mg/5ml generic name is Chlorpheniramine Maleate. Chlorpheniramine Maleate is an antihistamine medication used to relieve symptoms of allergic conditions such as hay fever, allergic conjunctivitis, and allergic skin conditions like hives and eczema. It works by blocking the action of histamine, which is a substance produced by the body during an allergic reaction. Chlorpheniramine Maleate is available as oral tablets and syrup, and it may also be found as an ingredient in some cold and flu medications. Common side effects can include drowsiness, dry mouth, and blurred vision. It's important to consult with a healthcare professional before taking Chlorpheniramine Maleate, especially if you have certain medical conditions or are taking other medications.

Indications

Pirafene 2mg/5ml Syrup is used for: Urticaria, Sneezing, Watery eyes, Allergic conditions, Anaphylactic shock, Rhinitis, Itching

Adult Dose

Oral Adult: 4 mg every 4-6 hr. Max: 24 mg daily. Parenteral Adjunct in the emergency treatment of anaphylactic shock Adult: 10-20 mg IM, SC, or slow IV inj over 1 min. Max dose: 40 mg daily.

Child Dose

Oral Child: 1-2 yr: 1 mg bid, 2-5 yr: 1 mg every 4-6 hr, 6-12 yr: 2 mg every 4-6 hr. Max: 6 mg daily (1-5 yr); 12 mg daily (6-12 yr). Parenteral Adjunct in the emergency treatment of anaphylactic shock Child: 87.5 mcg/kg SC 4 times daily

Renal Dose

Administration

Contra Indications

Hypersensitivity, Neonates.

Precautions

Elderly, pylori duodenal obstruction, angle-closure glaucoma, urinary retention, prostatic hyperplasia, epilepsy, renal and hepatic impairment. May affect performance of skilled tasks. BPH, bladder neck obstruction, hypertension. Pregnancy, lactation.

Pregnancy-Lactation

Pregnancy Antihistamine exposure in first trimester not reported to be associated with increased risk of malformations; animal studies not reported; there are no controlled data in human pregnancy; only recommended for use during pregnancy when benefit outweighs risk Lactation Excretion into human milk; the manufacturer recommends that caution be used when administering chlorpheniramine to nursing women; infants should be monitored for irritability or drowsiness; antihistamines may temporarily decrease maternal serum prolactin concentrations when administered prior to nursing infant for the first time

Interactions

Potentiates sedative effect of psychotropic drugs e.g. barbiturates, hypnotics, opioid analgesics, anxiolytics and antipsychotics. Interaction with alcohol could be dangerous (sedation/excitation).

Adverse Effects

Side effects of Chlorpheniramine Maleate : CNS depression, sedation, drowsiness, lassitude, dizziness. GI upsets, anorexia, or increased appetite, epigastric pain, blurring of vision, dysuria, dryness of mouth, tightness in chest, hypotension, muscular weakness, tinnitus, euphoria, headache, paradoxical CNS stimulation. Potentially Fatal: CV collapse and respiratory failure.

Mechanism of Action

Chlorphenamine is an H1-receptor antagonist which competetively blocks H1-receptor sites on tissues.

Note

Pirafene 2mg/5ml 2mg/5ml Syrup manufactured by THE MEMPHIS CHEMICAL CO.. Its generic name is Chlorpheniramine Maleate. Pirafene 2mg/5ml is availble in United Arab Emirates. Farmaco UAE drug index information on Pirafene 2mg/5ml Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Chlorpheniramine Maleate :

Tablets
Pirafene 4mg
THE MEMPHIS CHEMICAL CO.
Tablets
Pheniram 4mg
Medpharma Pharma. & Chem. Ind's (L.L.C)
Tablets
Pheniram 4mg
Medpharma Pharma. & Chem. Ind's (L.L.C)
Tablets
Omvil 4mg
National Pharmaceutical industries Co. (SAOG)
Syrup
Omvil 2mg/5ml 2mg/5ml
National Pharmaceutical industries Co. (SAOG)