Protussa Syrup
Dextromethorphan HBr, Chlorphenamine Maleate
Combination
Boots Co PLC
| Pack size | 120ml |
|---|---|
| Dispensing mode | SCD |
| Source | UK |
| Agent | AL BAKER TRADING EST. |
| Retail Price | 5.00 AED |
Indications
Protussa Syrup is used for:
DEXTROMETHORPHAN
For treatment and relief of dry cough
CHLORPHENAMINE
For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever
For treatment and relief of dry cough
CHLORPHENAMINE
For the treatment of rhinitis, urticaria, allergy, common cold, asthma and hay fever
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Dextromethorphan HBr, Chlorphenamine Maleate :
Mechanism of Action
DEXTROMETHORPHAN
Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the nmda glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier. The first-pass through the hepatic portal vein results in some of the drug being metabolized into an active metabolite of dextromethorphan, dextrorphan, the 3-hydroxy derivative of dextromethorphan
CHLORPHENAMINE
Chlorpheniramine binds to the histamine h1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine
Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the nmda glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier. The first-pass through the hepatic portal vein results in some of the drug being metabolized into an active metabolite of dextromethorphan, dextrorphan, the 3-hydroxy derivative of dextromethorphan
CHLORPHENAMINE
Chlorpheniramine binds to the histamine h1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine
Note
Protussa Combination Syrup manufactured by Boots Co PLC. Its generic name is Dextromethorphan HBr, Chlorphenamine Maleate. Protussa is availble in United Arab Emirates.
Farmaco UAE drug index information on Protussa Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.