PULVO-47 NEOMYCIN Topical Spray (Powder)
Catalase, Neomycin sulfate
"200000 Units, 28000 IU/g"
LABORATORIES URGO SOINS & SANTE
| Pack size | 4g Pressurised Bottle |
|---|---|
| Dispensing mode | POM |
| Source | FRANCE |
| Agent | ARABIAN ETHICALS CO. |
| Retail Price | 20.00 AED |
Indications
PULVO-47 NEOMYCIN Topical Spray (Powder) is used for:
Topical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives), treatment of otitis externa caused by susceptible bacteria, treatment or prevention of bacterial infections in skin lesions, and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy, as a perioperative prophylactic agent, and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC).
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Catalase, Neomycin sulfate :
Mechanism of Action
Aminoglycosides like neomycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes.
Note
PULVO-47 NEOMYCIN "200000 Units, 28000 IU/g" Topical Spray (Powder) manufactured by LABORATORIES URGO SOINS & SANTE. Its generic name is Catalase, Neomycin sulfate. PULVO-47 NEOMYCIN is availble in United Arab Emirates.
Farmaco UAE drug index information on PULVO-47 NEOMYCIN Topical Spray (Powder) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.