Radian B Topical Spray / Aerosol
Ammonium salicylate, Camphor, Menthol, Salicylic acid
Combination
RADIOL CHEMICALS LTD (FISON CONS. HEALTH)
| Pack size | 140ml Unit |
|---|---|
| Dispensing mode | P |
| Source | UK |
| Agent | AL RAZI PHARMACY |
| Retail Price | 6.00 AED |
Available as:
Indications
Radian B Topical Spray / Aerosol is used for:
AMMONIUM SALICYLATE
Temporary relief of minor aches and pains caused by arthritis, simple backache, strains, sprains, and bruises.
MENTHOL
Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.
SALICYLIC ACID
Key additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
Temporary relief of minor aches and pains caused by arthritis, simple backache, strains, sprains, and bruises.
MENTHOL
Used to treat occasional minor irritation, pain, sore mouth, and sore throat as well as cough associated with a cold or inhaled irritants.
SALICYLIC ACID
Key additive in many skin-care products for the treatment of acne, psoriasis, callouses, corns, keratosis pilaris and warts.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Ammonium salicylate, Camphor, Menthol, Salicylic acid :
Mechanism of Action
MENTHOL
Menthol primarily activates the cold-sensitive trpm8 receptors in the skin. Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting ca++ currents of neuronal membranes. It may also yield analgesic properties via kappa-opioid receptor agonism.
SALICYLIC ACID
Salicylic acid directly and irreversibly inhibits the activity of both types of cyclo-oxygenases (cox-1 and cox-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid. Salicylate may competitively inhibit prostaglandin formation. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms. Salicylic acid is a key ingredient in many skin-care products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. It works by causing the cells of the epidermis to slough off more readily, preventing pores from clogging up, and allowing room for new cell growth. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. Salicylic acid is also used as an active ingredient in gels which remove verrucas (plantar warts). Salicylic acid inhibits the oxidation of uridine-5-diphosphoglucose (udpg) competitively with nicotinamide adenosine dinucleotide (nad) and noncompetitively with udpg. It also competitively inhibits the transferring of glucuronyl group of uridine-5-phosphoglucuronic acid (udpga) to the phenolic acceptor. The wound-healing retardation action of salicylates is probably due mainly to its inhibitory action on mucopolysaccharide synthesis.
Menthol primarily activates the cold-sensitive trpm8 receptors in the skin. Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting ca++ currents of neuronal membranes. It may also yield analgesic properties via kappa-opioid receptor agonism.
SALICYLIC ACID
Salicylic acid directly and irreversibly inhibits the activity of both types of cyclo-oxygenases (cox-1 and cox-2) to decrease the formation of precursors of prostaglandins and thromboxanes from arachidonic acid. Salicylate may competitively inhibit prostaglandin formation. Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms. Salicylic acid is a key ingredient in many skin-care products for the treatment of acne, psoriasis, calluses, corns, keratosis pilaris, and warts. It works by causing the cells of the epidermis to slough off more readily, preventing pores from clogging up, and allowing room for new cell growth. Because of its effect on skin cells, salicylic acid is used in several shampoos used to treat dandruff. Salicylic acid is also used as an active ingredient in gels which remove verrucas (plantar warts). Salicylic acid inhibits the oxidation of uridine-5-diphosphoglucose (udpg) competitively with nicotinamide adenosine dinucleotide (nad) and noncompetitively with udpg. It also competitively inhibits the transferring of glucuronyl group of uridine-5-phosphoglucuronic acid (udpga) to the phenolic acceptor. The wound-healing retardation action of salicylates is probably due mainly to its inhibitory action on mucopolysaccharide synthesis.
Note
Radian B Combination Topical Spray / Aerosol manufactured by RADIOL CHEMICALS LTD (FISON CONS. HEALTH). Its generic name is Ammonium salicylate, Camphor, Menthol, Salicylic acid. Radian B is availble in United Arab Emirates.
Farmaco UAE drug index information on Radian B Topical Spray / Aerosol is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.