Relpax Tablets / Film-coated

Eletriptan (as HBr)
20mg
PFIZER GmbH
Pack size 3's Blister
Dispensing mode POM
Source GERMANY
AgentAL BAKER TRADING EST.
Retail Price 85.50 AED

Indications

Relpax Tablets / Film-coated is used for: For the acute treatment of migraine with or without aura in adults.

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Eletriptan (as HBr) :

Mechanism of Action

Eletriptan binds with high affinity to 5-HT1B, 5-HT1D and 5-HT1F receptors, has modest affinity for 5-HT1A, 5-HT1E, 5-HT2B and 5-HT7 receptors, and little or no affinity for 5-HT2A, 5-HT2C, 5-HT3, 5-HT4, 5-HT5A and 5-HT6 receptors. Eletriptan has no significant affinity or pharmacological activity at adrenergic alpha1, alpha2, or beta; dopaminergic D1 or D2; muscarinic; or opioid receptors. Two theories have been proposed to explain the efficacy of 5-HT receptor agonists in migraine. One theory suggests that activation of 5-HT1 receptors located on intracranial blood vessels, including those on the arteriovenous anastomoses, leads to vasoconstriction, which is correlated with the relief of migraine headache. The other hypothesis suggests that activation of 5-HT1 receptors on sensory nerve endings in the trigeminal system results in the inhibition of pro-inflammatory neuropeptide release.

Note

Relpax 20mg Tablets / Film-coated manufactured by PFIZER GmbH. Its generic name is Eletriptan (as HBr). Relpax is availble in United Arab Emirates. Farmaco UAE drug index information on Relpax Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Eletriptan (as HBr) :