Rinosin Eye / Ear Drops
Chlorpheniramine maleate, Naphazoline HCl
"0.5mg, 0.5mg/ml"
Pharco Pharmaceuticals
Pack size | 10ml Dropper Bottle |
---|---|
Dispensing mode | POM |
Source | EGYPT |
Agent | GULF DRUG EST. |
Retail Price | 4.50 AED |
Indications
Rinosin Eye / Ear Drops is used for:
PHENIRAMINE
Pheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria
NAPHAZOLINE
Naphazoline is primarily indicated in conditions like corneal vascularity, hyperaemia, itching, nasal congestion, and can also be given in adjunctive therapy as an alternative drug of choice in sinusitis
Pheniramine is an antihistamine used to treat allergic conditions such as hay fever or urticaria
NAPHAZOLINE
Naphazoline is primarily indicated in conditions like corneal vascularity, hyperaemia, itching, nasal congestion, and can also be given in adjunctive therapy as an alternative drug of choice in sinusitis
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Chlorpheniramine maleate, Naphazoline HCl :
Mechanism of Action
PHENIRAMINE
Antihistamines such as pheniramine appear to compete with histamine for histamine h1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of h1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. Antihistamines suppress the histamine-induced wheal (swelling) and flare (vasodilation) response by blocking the binding of histamine to its receptors on nerves, vascular smooth muscle, glandular cells, endothelium, and mast cells. They effectively exert competitive antagonism of histamine for h1-receptors
NAPHAZOLINE
Naphazoline is a direct acting sympathomimetic drug, which acts on alpha-adrenergic receptors in the arterioles of the nasal mucosa. This activates the adrenal system to yield systemic vasoconstrction. In producing vasoconstriction, the result is a decrease in blood flow in the nasal passages and consequently decreased nasal congestion. The vasoconstriction means that there is less pressure in the capillaries and less water can filter out, thus less discharge is made
Antihistamines such as pheniramine appear to compete with histamine for histamine h1- receptor sites on effector cells. The antihistamines antagonize those pharmacological effects of histamine which are mediated through activation of h1- receptor sites and thereby reduce the intensity of allergic reactions and tissue injury response involving histamine release. Antihistamines suppress the histamine-induced wheal (swelling) and flare (vasodilation) response by blocking the binding of histamine to its receptors on nerves, vascular smooth muscle, glandular cells, endothelium, and mast cells. They effectively exert competitive antagonism of histamine for h1-receptors
NAPHAZOLINE
Naphazoline is a direct acting sympathomimetic drug, which acts on alpha-adrenergic receptors in the arterioles of the nasal mucosa. This activates the adrenal system to yield systemic vasoconstrction. In producing vasoconstriction, the result is a decrease in blood flow in the nasal passages and consequently decreased nasal congestion. The vasoconstriction means that there is less pressure in the capillaries and less water can filter out, thus less discharge is made
Note
Rinosin "0.5mg, 0.5mg/ml" Eye / Ear Drops manufactured by Pharco Pharmaceuticals. Its generic name is Chlorpheniramine maleate, Naphazoline HCl. Rinosin is availble in United Arab Emirates.
Farmaco UAE drug index information on Rinosin Eye / Ear Drops is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.