ROVAMYCINE Tablets / film-coated

Spiramycine
3 MIU
SANOFI AVENTIS
Pack size 10's (5's Blister x 2)
Dispensing mode POM
Source FRANCE
AgentModern Pharmaceutical Co.
Retail Price 32.50 AED

Indications

ROVAMYCINE Tablets / film-coated is used for: Susceptible infections, Cryptosporidiosis, Toxoplasmosis, Protozoal infections

Adult Dose

Oral Toxoplasmosis; Protozoal infections; Cryptosporidiosis; Susceptible infections Adult: 6-9 million units/day in 2-3 divided doses, increased to 15 million units/day, given in divided doses for severe infections.

Child Dose

Oral Child and Neonates: Chemoprophylaxis of congenital toxoplasmosis: 50 mg/kg bid.

Renal Dose

Administration

May be taken with or without food.

Contra Indications

Hypersensitivity.

Precautions

Hepatic impairment; pregnancy and lactation. Monitor liver function. History of arrhythmias or predisposition to QT interval prolongation.

Pregnancy-Lactation

Interactions

Decreases carbidopa absorption and levodopa concentrations. Increased risk of ventricular arrhythmias when used with astemizole, cisapride and terfenadine. Risk of acute dystonia when used with fluphenazine.

Adverse Effects

Side effects of Spiramycine : Nausea, vomiting, abdominal pain, diarrhoea; urticaria, pruritus, macular rashes. Transient paraesthesia may occur. Potentially Fatal: Pseudomembranous colitis; anaphylaxis; neuromuscular blockade; ventricular arrhythmias, prolongation of QT interval.

Mechanism of Action

Spiramycin is a macrolide antibacterial that inhibits protein synthesis by irreversibly binding to the 50S subunit of the ribosomal subunit thus blocking the transpeptidation or translocation reactions of susceptible organisms resulting in stunted cell growth

Note

ROVAMYCINE 3 MIU Tablets / film-coated manufactured by SANOFI AVENTIS. Its generic name is Spiramycine. ROVAMYCINE is availble in United Arab Emirates. Farmaco UAE drug index information on ROVAMYCINE Tablets / film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Spiramycine :