SALAZOPYRIN EN -TABS _ Tablets

Sulfasalazine (as combination with polyvidone)
500mg
PHARMACIA & UPJOHN AB.
Pack size 100's Bottle
Dispensing mode POM
Source SWEDEN
AgentGULF DRUG EST.
Retail Price 38.50 AED

Indications

SALAZOPYRIN EN -TABS _ Tablets is used for: For the treatment of Crohn's disease and rheumatoid arthritis as a second-line agent.

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Sulfasalazine (as combination with polyvidone) :

Mechanism of Action

The mode of action of Sulfasalazine or its metabolites, 5-aminosalicylic acid (5-ASA) and sulfapyridine (SP), is still under investigation, but may be related to the anti-inflammatory and/or immunomodulatory properties that have been observed in animal and in vitro models, to its affinity for connective tissue, and/or to the relatively high concentration it reaches in serous fluids, the liver and intestinal walls, as demonstrated in autoradiographic studies in animals. In ulcerative colitis, clinical studies utilizing rectal administration of Sulfasalazine, SP and 5-ASA have indicated that the major therapeutic action may reside in the 5-ASA moiety. The relative contribution of the parent drug and the major metabolites in rheumatoid arthritis is unknown.

Note

SALAZOPYRIN EN -TABS _ 500mg Tablets manufactured by PHARMACIA & UPJOHN AB.. Its generic name is Sulfasalazine (as combination with polyvidone). SALAZOPYRIN EN -TABS _ is availble in United Arab Emirates. Farmaco UAE drug index information on SALAZOPYRIN EN -TABS _ Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Sulfasalazine (as combination with polyvidone) :