SAPOFEN COLD & FLU Tablets / Film-coated
Ibuprofen + Pseudoephedrine
"200mg, 30mg"
SPIMACO (Al Qassim Pharmaceutical Plant)
| Pack size | 20's (10's Blister x 2) |
|---|---|
| Dispensing mode | POM |
| Source | SAUDI ARABIA |
| Agent | CITY MEDICAL STORE |
| Retail Price | 9.00 AED |
Indications
SAPOFEN COLD & FLU Tablets / Film-coated is used for:
Cold Symptoms
Adult Dose
Child Dose
Cold Symptoms
<12 years: Safety and efficacy not established
>12 years: 1 caplet/capsule PO q4-6hr PRN; may increase to 2 caplets/capsules q4-6hr if necessary while symptoms persist Not to exceed 6 doses/24 hr
Renal Dose
Administration
Take with food or milk if stomach upset occurs
Contra Indications
Hypersensitivity
Immediately before or after heart surgery
History of induce asthma or urticaria with NSAIDs
Do not use with MAO inhibitors or for 2 weeks after discontinuing MAO inhibitors because of risk for hypertensive crisis
Precautions
Caution with hypertension, heart disease, hepatic or renal impairment, asthma, thyroid disease, diabetes, BPH, peptic ulcer disease
NSAID content
May increase risk for GI ulceration, increased risk if age >60 yr or history of PUD
Caution in coadministration with antiplatelets/anticoagulants
May decrease benefit of cardioprotective low-dose aspirin
NSAIDS, except aspirin, increase risk of heart attack, heart failure, and stroke; which can be fatal; the risk is higher if patients use more than it was directed or for longer than needed
Use caution in patients with high blood pressure, heart disease, liver cirrhosis, kidney disease, asthma, thyroid disease, diabetes, glaucoma, have trouble urinating due to an enlarged prostate gland, or had a stroke
Patients should inform healthcare professional if they have symptoms of heart problems or stroke, chest pain, trouble breathing, weakness in one part or side of body, slurred speech, leg swelling
Pseudoephedrine
May exacerbate poorly controlled hypertension
Caution if underlying cardiovascular risks present
Pregnancy-Lactation
Pregnancy & Lactation
Do not take NSAIDs within 3 months before delivery because of risk for premature closure of the ductus arteriosus
Lactation: NSAIDs and pseudoephedrine excreted in breast milk, AAP states compatible with breastfeeding
Interactions
Adverse Effects
Side effects of Ibuprofen + Pseudoephedrine :
Frequency Not Defined
GI upset
Insomnia
Arrhythmia
Palpitations
Convulsion
Dizziness
Drowsiness
Excitability
Headache
Tremor
Weakness
NauseaVomiting
Hemolytic anemia
Aplastic anemia
Arrhythmia
Bronchospasm
CHF
Efoliative dermatitis
Constipation
Hypertension
Neutropenia
Thromboembolism
Abdominal pain
Anxiety
CNS stimulation
Hepatotoxicity
Dizziness
Mechanism of Action
Ibuprofen: Inhibits synthesis of prostaglandins by inhibiting cyclooxygenase (COX-1, COX-2); may inhibit chemotaxis, alter lymphocyte activity, decrease proinflammatory cytoking activity, and inhibit neutrophil aggregation, which in turn may result in anti-inflammatory activity
Pseudoephedrine stimulates the alpha-adrenergic receptors causing bronchodilation and vasoconstriction
Note
SAPOFEN COLD & FLU "200mg, 30mg" Tablets / Film-coated manufactured by SPIMACO (Al Qassim Pharmaceutical Plant). Its generic name is Ibuprofen + Pseudoephedrine. SAPOFEN COLD & FLU is availble in United Arab Emirates.
Farmaco UAE drug index information on SAPOFEN COLD & FLU Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Some other brands of Ibuprofen + Pseudoephedrine :
Capsules (Soft Gelatin)
Pseudoflam
200mg/30mg
Pharmax Pharmaceuticals FZ LLC
Tablets / Film-coated
PROFINAL COLD & SINUS
"200mg, 30mg"
Julphar (Gulf Pharmaceutical Industries)
Tablets / Film-coated
NUROFEN COLD AND FLU
"200mg, 30mg"
CROOKES HEALTHCARE
Tablets / Film-coated
NUROFEN COLD AND FLU
"200mg, 30mg"
CROOKES HEALTHCARE
Tablets (Caplets) / Coated
ADVIL COLD & SINUS
"200mg, 30mg"
WYETH CANADA