Sedofan Tablets
Pseudoephedrine + Triprolidine
"60mg, 2.5mg"
Julphar (Gulf Pharmaceutical Industries)
| Pack size | 30's (10's Blister x 3) |
|---|---|
| Dispensing mode | POM |
| Source | UAE |
| Agent | JULPHAR |
| Retail Price | 12.00 AED |
Available as:
Indications
Sedofan Tablets is used for:
Pneumonia, Pharyngitis, Allergic rhinitis, Upper respiratory tract, Dry cough, Tracheolaryngitis
Adult Dose
Oral
Allergic rhinitis, Cold and flu
Adult: Each tablet contains triprolidine HCl 2.5 mg and pseudoephedrine HCl 60 mg: 1 tablet 4-6 hrly, up to 4 times a day.
Child Dose
Oral
Allergic rhinitis, Cold and flu
Child > 12 yr: 1 tablet 4-6 hrly, up to 4 times a day.
Renal Dose
Administration
Contra Indications
Concurrent use or within 2 wk of stopping MAOIs. Severe hypertension or coronary artery disease.
Precautions
Severe hepatic impairment. Moderate to severe renal impairment. DM, hyperthyroidism, increased intraocular pressure, prostatic hypertrophy, hypertension, heart disease. May affect ability to drive or operate machinery. Pregnancy and lactation.
Pregnancy-Lactation
Interactions
Increased BP with other sympathomimetic agents (e.g. decongestants, TCA, appetite suppressants). Reduced hypotensive effects of methyldopa, ?- and ?-adrenergic blockers. Increased side effects (e.g. somnolence, agitation) with atomoxetine.
Potentially Fatal: Increased risk of hypertensive crisis with furazolidine, avoid concurrent use. Increased risk of hypertensive crisis with MAOIs; avoid concurrent use or within 2 wk after stopping MAOIs. Increased risk of psychosis with bromocriptine.
Adverse Effects
Side effects of Pseudoephedrine + Triprolidine :
Dry mouth, nose and throat; skin rashes, tachycardia, drowsiness, sleep disturbances, urinary retention. Rarely, hallucinations.
Mechanism of Action
Triprolidine hydrochloride is a potent competitive histamine H1-receptor antagonist with antimuscarinic and mild sedative properties. Pseudoephedrine, an alpha- and beta-adrenergic receptor agonist, mediates vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa.
Note
Sedofan "60mg, 2.5mg" Tablets manufactured by Julphar (Gulf Pharmaceutical Industries). Its generic name is Pseudoephedrine + Triprolidine. Sedofan is availble in United Arab Emirates.
Farmaco UAE drug index information on Sedofan Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.