Silosin Capsules (Hard Gelatin)
Silodosin
4mg
Algorithm S.A.L.
| Pack size | 30's (10's Blister x 3) |
|---|---|
| Dispensing mode | POM |
| Source | LEBANON |
| Agent | CITY MEDICAL STORE |
| Retail Price | 101.50 AED |
Available as:
Indications
Silosin Capsules (Hard Gelatin) is used for:
Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).
Adult Dose
Benign Prostatic Hyperplasia
Adults
PO 8 mg once daily with a meal.
Hepatic Impairment
Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary
Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)
Child Dose
Renal Dose
Renal Impairment
CrCl <50 mL/min: Dose adjustment not necessary
CrCl 30-50 mL/min: 4 mg PO qDay
CrCl <30 mL/min: Contraindicated
Administration
Contra Indications
Hypersensitivity.
Precautions
Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).
Pregnancy-Lactation
Pregnancy Category: B; not indicated in women
Lactation: Unknown if distributed in breast milk; not indicated in women
Interactions
Ketoconazole, digoxin.
Adverse Effects
Side effects of Silodosin :
>10%
Retrograde ejaculation (28%)
1-10%
Diarrhea (3%), Headache (2%), Insomnia ((1-2%), Dizziness (3%), Orthostatic hypotension (3%; increased in patients >65 years), Nasopharyngitis (2%), Nasal congestion (2%), Sinusitis (1-2%)
Mechanism of Action
Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.
Note
Silosin 4mg Capsules (Hard Gelatin) manufactured by Algorithm S.A.L.. Its generic name is Silodosin. Silosin is availble in United Arab Emirates.
Farmaco UAE drug index information on Silosin Capsules (Hard Gelatin) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.