Silosin Capsules (Hard Gelatin)

Silodosin
4mg
Algorithm S.A.L.
Pack size 30's (10's Blister x 3)
Dispensing mode POM
Source LEBANON
AgentCITY MEDICAL STORE
Retail Price 101.50 AED

Indications

Silosin Capsules (Hard Gelatin) is used for: Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).

Adult Dose

Benign Prostatic Hyperplasia Adults PO 8 mg once daily with a meal. Hepatic Impairment Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)

Child Dose

Renal Dose

Renal Impairment CrCl <50 mL/min: Dose adjustment not necessary CrCl 30-50 mL/min: 4 mg PO qDay CrCl <30 mL/min: Contraindicated

Administration

Contra Indications

Hypersensitivity.

Precautions

Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).

Pregnancy-Lactation

Pregnancy Category: B; not indicated in women Lactation: Unknown if distributed in breast milk; not indicated in women

Interactions

Ketoconazole, digoxin.

Adverse Effects

Side effects of Silodosin : >10% Retrograde ejaculation (28%) 1-10% Diarrhea (3%), Headache (2%), Insomnia ((1-2%), Dizziness (3%), Orthostatic hypotension (3%; increased in patients >65 years), Nasopharyngitis (2%), Nasal congestion (2%), Sinusitis (1-2%)

Mechanism of Action

Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.

Note

Silosin 4mg Capsules (Hard Gelatin) manufactured by Algorithm S.A.L.. Its generic name is Silodosin. Silosin is availble in United Arab Emirates. Farmaco UAE drug index information on Silosin Capsules (Hard Gelatin) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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