Sudafed Tablets
Pseudoephedrine Hydrochloride
60mg
The Wellcome Foundation Limited
| Pack size | 100's |
|---|---|
| Dispensing mode | POM |
| Source | UK |
| Agent | AL BAKER TRADING EST. |
| Retail Price | 31.00 AED |
Indications
Sudafed Tablets is used for:
Nasal congestion
Adult Dose
Oral
Nasal congestion
Adult: 1 tablet (60 mg) every 4-6 hr. Max: 4 tab in 24 hr.
Child Dose
Oral
Nasal congestion
Children : 6 - 12 years of age: 1/2 tablet (30 mg) 3-4 times daily.
2 - 5 years of age: 1/4 tablet (15 mg) every 3-4 times daily.
Renal Dose
Administration
May be taken with or without food.
Contra Indications
Hypersensitivity, Severe hypertension and coronary artery disease, Concurrent use of Mono Amine Oxidase Inhibitor (MAOI) drugs.
Precautions
Hyperthyroidism; ischaemic heart disease, arrhythmia or tachycardia; occlusive vascular disorders e.g. arteriosclerosis, hypertension or aneurysms; DM and closed-angle glaucoma; renal impairment, prostatic enlargement. Pregnancy; lactation.
Lactation: Concentrated in breast milk, Mfr contraindicates (AAP Committee states compatible with nursing)
Pregnancy-Lactation
Pregnancy
Avoid, during first trimester; may be associated with possible risk of gastroschisis, small intestinal atresia, and hemifacial microsomia due to pseudoephedrine’s vasoconstrictive effects; magnitude of risk unknown
Fetal tachycardia reported following maternal use of extended release formulation for multiple days
Lactation
Excreted in breast milk; irritability reported in nursing infants (limited data); milk production may be decreased in some women
Interactions
Increased risk of hypertension and arrhythmias if given with cardiac glycosides, quinidine or TCAs. Increased risk of vasoconstrictor effects if given with ergot alkaloids or oxytocin. Co-admin with MAOIs may cause hypertensive crisis. Anaesthetics e.g. cyclopropane, halothane and other halogenated anaesthestics; antihypertensive agents.
Adverse Effects
Side effects of Pseudoephedrine Hydrochloride :
Anginal pain; rebound congestion and rhinorrhoea; fear, anxiety, restlessness, tremor, insomnia, confusion, irritability and psychotic states; reduced appetite, nausea, vomiting; gangrene; cerebral haemorrhage and pulmonary oedema; reflex bradycardia, tachycardia and cardiac arrhythmias, palpitations and cardiac arrest, hypotension and dizziness, fainting and flushing. Tissue necrosis and sloughing; myocardial and arterial necrosis.
Mechanism of Action
Pseudoephedrine is both an alpha-and beta-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa. It also directly stimulates beta-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility.
Note
Sudafed 60mg Tablets manufactured by The Wellcome Foundation Limited. Its generic name is Pseudoephedrine Hydrochloride. Sudafed is availble in United Arab Emirates.
Farmaco UAE drug index information on Sudafed Tablets is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.