Synbon Capsules (Hard Gelatin) / Modified Release
Mebeverine Hydrochloride
200mg
Neopharma
| Pack size | 30's (10's Blister x 3) |
|---|---|
| Dispensing mode | POM |
| Source | UAE |
| Agent | ALPHAMED DRUG STORE |
| Retail Price | 36.50 AED |
Indications
Synbon Capsules (Hard Gelatin) / Modified Release is used for:
Irritable bowel syndrome (IBS), GI tract spasm
Adult Dose
Oral
Irritable bowel syndrome; Gastrointestinal tract spasm
Adult:
Tablet 135 mg tid, may reduce gradually after several wk when the desired effect has been obtained;
As modified-release Capsule: 200 mg bid.
Child Dose
Renal Dose
Administration
Contra Indications
Paralytic ileus.
Precautions
Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.
Pregnancy-Lactation
Pregnancy
Contraindicated during pregnancy; avoid pregnancy for 3 months following vaccination
In a 10-year survey involving over 700 pregnant women who received rubella vaccine within 3 months before or after conception (of whom 189 received the Wistar RA 27/3 strain), none of the newborns had abnormalities compatible with congenital rubella syndrome
Mumps infection during the first trimester of pregnancy may increase the rate of spontaneous abortion
Although mumps vaccine virus has been shown to infect the placenta and fetus, there is no evidence that it causes congenital malformations in humans
Reports have indicated that contracting wild-type measles during pregnancy enhances fetal risk; increased rates of spontaneous abortion, stillbirth, congenital defects and prematurity have been observed subsequent to infection with wild-type measles during pregnancy
There are no adequate studies of the attenuated (vaccine) strain of measles virus in pregnancy; however, it would be prudent to assume that the vaccine strain of virus is also capable of inducing adverse fetal effects
Lactation
Unknown if measles or mumps vaccine is secreted in human milk
The prescribing information describes studies that have shown lactating postpartum women immunized with live attenuated rubella vaccine may secrete the virus in breast milk and transmit it to breastfed infants
Interactions
Adverse Effects
Side effects of Mebeverine Hydrochloride :
Dizziness, headache, GI disturbances, insomnia, anorexia, decreased heart rate, hypersensitivity (e.g. urticaria, erythematous rash, angioedema).
Mechanism of Action
Mebeverine is an antispasmodic agent which exerts direct action on the GI smooth muscle.
Note
Synbon 200mg Capsules (Hard Gelatin) / Modified Release manufactured by Neopharma. Its generic name is Mebeverine Hydrochloride. Synbon is availble in United Arab Emirates.
Farmaco UAE drug index information on Synbon Capsules (Hard Gelatin) / Modified Release is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.