Terfina 1% Cream

Terbinafine Topical
10mg/g
Oman Pharmaceutical Products
Pack size 15g Collapsible Tube
Dispensing mode POM
Source OMAN
AgentMuscat Pharmaceutical Trading L.L.C.
Retail Price 22.50 AED

Indications

Terfina 1% Cream is used for: Tinea pedis, Tinea cruris, Tinea corporis, Dermatophytosis, Nail infections, Cutaneous candidiasis, Pityriasis versicolor

Adult Dose

Topical/Cutaneous As cream or spray Dermatophytosis Adult: Tinea Pedis: Apply to affected area BID until significant clinical improvement (no more than 4 weeks) Tinea Corporis & Cruris: Apply once daily, for 1 week, (no more than 4 weeks) Cutaneous candidiasis and pityriasis versicolor: Apply once or bid for 2 wk

Child Dose

Not FDA approved for peds

Renal Dose

Administration

Contra Indications

Hypersensitivity, active or chronic liver disease, lactation.

Precautions

Preexisting liver or renal impairment, pregnancy. Perform liver function tests prior to oral therapy. Lactation: not safe for nursing infants

Pregnancy-Lactation

Pregnancy Category: B Lactation: not safe for nursing infants

Interactions

Possible increase in levels in drugs metabolised by CYP450 2D6. Decreased terbinafine concentration with rifampicin; increased terbinafine concentration with cimetidine.

Adverse Effects

Side effects of Terbinafine Topical : 1-10% Burning, Contact dermatitis, Dryness, Exfoliation, Irritation, Pruritus, Rash, Irritation, Stinging Potentially Fatal: Liver failure, Stevens-Johnson syndrome, neutropaenia.

Mechanism of Action

Terbinafine causes fungal cell death by inhibiting squalene epoxidase, the main enzyme in sterol biosynthesis, resulting in ergosterol deficiency within fungal cell walls. It has fungicidal activity against dermatophytes and some yeast.

Note

Terfina 1% 10mg/g Cream manufactured by Oman Pharmaceutical Products. Its generic name is Terbinafine Topical. Terfina 1% is availble in United Arab Emirates. Farmaco UAE drug index information on Terfina 1% Cream is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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