TREDAPTIVE 1000/20mg Tablets / Modified Release
Niacin (Nicotinic acid), Laropiprant
"1g, 20mg"
Merck Sharp & Dohme Limited
| Pack size | 28's (7's Blister x 4) |
|---|---|
| Dispensing mode | POM |
| Source | UK |
| Agent | CITY MEDICAL STORE |
| Retail Price | 112.50 AED |
Available as:
Indications
TREDAPTIVE 1000/20mg Tablets / Modified Release is used for:
Laropiprant itself has no cholesterol lowering effect, but it reduces facial flushes induced by niacin
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Niacin (Nicotinic acid), Laropiprant :
Mechanism of Action
Niacin in cholesterol lowering doses (500<2000 mg per day) causes facial flushes by stimulating biosynthesis of prostaglandin D2 (PGD2), especially in the skin. PGD2 dilates the blood vessels via activation of prostaglandin D2 receptors (DP1), increasing blood flow and thus leading to flushes. Laropiprant acts as a selective DP1 antagonist, reducing the vasodilation
Note
TREDAPTIVE 1000/20mg "1g, 20mg" Tablets / Modified Release manufactured by Merck Sharp & Dohme Limited. Its generic name is Niacin (Nicotinic acid), Laropiprant. TREDAPTIVE 1000/20mg is availble in United Arab Emirates.
Farmaco UAE drug index information on TREDAPTIVE 1000/20mg Tablets / Modified Release is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.