Tylenol Rectal Suppositories

Pack size 10's Blister
Dispensing mode P
Retail Price 13.00 AED

Tylenol Overview

Tylenol generic name is Paracetamol. Paracetamol is a commonly used over-the-counter medication that is used to relieve pain and reduce fever. It works by blocking the production of certain chemicals in the body that can cause pain and inflammation. Paracetamol is available as an oral tablet, capsule, and liquid form, as well as a rectal suppository. It can also be found in combination with other medications such as opioids and caffeine. Paracetamol is generally considered safe when used as directed and has fewer side effects than other pain-relieving medications such as non-steroidal anti-inflammatory drugs (NSAIDs). However, taking more than the recommended dose or taking it for long periods of time can cause liver damage. It's important to follow the recommended dosage and not to exceed the maximum daily dose, which is generally 4,000 milligrams per day for adults. Also, it's essential to inform your doctor if you are taking other medications, have any pre-existing medical conditions, pregnant or breastfeeding.


Tylenol Rectal Suppositories is used for: Fever, Mild to moderate pain, osteoarthritis, rheumatoid arthritis, chronic low back pain, Renal stone pain, neuropathic pain, toothache, migraine, postoperative mild to moderate pain.

Adult Dose

Oral Mild to moderate pain and fever Tablet Adult: 1 - 2 tablets every 4 to 6 hours up to a maximum of 4 g (8 tablets) daily Extended Release (XR) Tablet Adults: 2 tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours). Syrup/Suspension: Adults: 4-8 Measuring spoonful 3-4 times daily; Rectal Suppository Adults: 500 mg-1 g every 4-6 hours to a maximum of 4 g daily.

Child Dose

Oral Mild to moderate pain and fever Tablet Children (6 - 12 years) : 1/2 to 1 tablet 3 to 4 times daily Extended Release (XR) Tablet Children over 12 years: 2 tablets, swallowed whole, every 6 to 8 hours (maximum of 6 tablets in any 24 hours). Syrup Mild to moderate pain and fever Children: 3 months - <1 year : 60 - 120 mg (1/2 - 1 measuring spoonful), 1 - 5 years : 1 - 2 measuring spoonful 6 - 12 years : 2 - 4 measuring spoonful Children: 2 months: 60 mg (1/2 measuring spoonful) for post immunization pyrexia; Paediatric Drops Mild to moderate pain and fever Children Up to 3 months: 0.5 ml (40 mg) 4 to 11 months: 1.0 ml (80 mg) 1 to <2 years: 1.5 ml (120 mg) 2 to 3 years: 2 ml (160mg) 4 to 5 years: 3 ml (240 mg) Dose can be repeated, every 4 hours. Rectal Mild to moderate pain and fever Suppository Children: 3 months-<1 year: 60-125 mg 1-<5 years: 125-250 mg 5-12 years: 250-500 mg These doses may be repeated every 4-6 hours as necessary (maximum 4 doses in 24 hours). Children over 12 years: 500 mg-1 g every 4-6 hours to a maximum of 4 g daily. Post-immunisation pyrexia Child: 2-3 mth 60 mg. If necessary, a 2nd dose may be given after 4-6 hr.

Renal Dose


May be taken with or without food.

Contra Indications



Patient w/ chronic alcoholism, known G6PD deficiency, severe hypovolaemia, chronic malnutrition. Renal and hepatic impairment. Pregnancy and lactation. Monitoring Parameters Monitor serum paracetamol levels esp when acute overdosage is suspected and w/ long-term use.


Pregnancy Drug crosses placenta and can be detected in cord blood, newborn serum, and urine immediately after delivery Increased risk of teratogenic effects not reported following maternal use of drug during pregnancy Use of normal doses during pregnancy not associated with increased risk of miscarriage or still birth; however, increase in fetal death or spontaneous abortion may be seen with maternal overdose if treatment delayed Wheezing and asthma in early childhood associated with frequent maternal use of drug during pregnancy Lactation Drug is excreted in milk; in general, breastfeeding is generally acceptable if relative infant dose (RID) is <10%; avoid breastfeeding when RID>25%


May reduce serum levels w/ anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin and other coumarins w/ prolonged use. Accelerated absorption w/ metoclopramide and domperidone. May increase serum levels w/ probenecid. May increase serum levels of chloramphenicol. May reduce absorption w/ colestyramine w/in 1 hr of admin. May cause severe hypothermia w/ phenothiazine.

Adverse Effects

Side effects of Paracetamol : Thrombocytopenia, leucopenia, pancytopenia, neutropenia, agranulocytosis, pain and burning sensation at inj site. Rarely, hypotension and tachycardia. Potentially Fatal: Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalised exanthematous pustulosis, acute renal tubular necrosis and hepatotoxicity.

Mechanism of Action

Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heat-regulating centre. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS.


Tylenol 350mg Rectal Suppositories manufactured by CILAG AG. Its generic name is Paracetamol. Tylenol is availble in United Arab Emirates. Farmaco UAE drug index information on Tylenol Rectal Suppositories is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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