Unicycline Capsules (Hard Gelatin)
Demiclocycline
NA
PINEWOOD LAB. (CONMED)
| Pack size | 6's |
|---|---|
| Dispensing mode | POM |
| Source | IRELAND |
| Agent | AL MAFRAQ PHARMACEUTICAL EST. |
| Retail Price | 13.50 AED |
Indications
Unicycline Capsules (Hard Gelatin) is used for:
Used primarily to treat Lyme disease, acne, and bronchitis. Also indicated (but rarely used) to treat urinary tract infections, gum disease, malaria, and other bacterial infections such as gonorrhea and chlamydia. One of its other registered uses is the treatment of hyponatremia (low blood sodium concentration) due to the syndrome of inappropriate antidiuretic hormone (SIADH) where fluid restriction alone has been ineffective.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Demiclocycline :
Mechanism of Action
Demeclocycline inhibits cell growth by inhibiting translation. It binds (reversibly) to the 30S and 50S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome, which impairs protein synthesis by bacteria. The binding is reversible in nature. The use in SIADH actually relies on a side-effect of tetracycline antibiotics; many may cause diabetes insipidus (dehydration due to the inability to concentrate urine). It is not completely understood why demeclocycline impairs the action of antidiuretic hormone, but it is thought that it blocks the binding of the hormone to its receptor.
Note
Unicycline NA Capsules (Hard Gelatin) manufactured by PINEWOOD LAB. (CONMED). Its generic name is Demiclocycline. Unicycline is availble in United Arab Emirates.
Farmaco UAE drug index information on Unicycline Capsules (Hard Gelatin) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.