Unifed Syrup

Pseudoephedrine + Triprolidine
"30mg, 1.25mg/5ml"
THE UNITED PHARMACEUTICAL MANUFACTURING CO. LTD.
Pack size 120ml Glass Bottle
Dispensing mode POM
Source JORDAN
AgentARABIAN ETHICALS CO.
Retail Price 5.50 AED

Indications

Unifed Syrup is used for: Pneumonia, Pharyngitis, Allergic rhinitis, Upper respiratory tract, Dry cough, Tracheolaryngitis

Adult Dose

Oral Allergic rhinitis, Cold and flu Adult: Each tablet contains triprolidine HCl 2.5 mg and pseudoephedrine HCl 60 mg: 1 tablet 4-6 hrly, up to 4 times a day.

Child Dose

Oral Allergic rhinitis, Cold and flu Child > 12 yr: 1 tablet 4-6 hrly, up to 4 times a day.

Renal Dose

Administration

Contra Indications

Concurrent use or within 2 wk of stopping MAOIs. Severe hypertension or coronary artery disease.

Precautions

Severe hepatic impairment. Moderate to severe renal impairment. DM, hyperthyroidism, increased intraocular pressure, prostatic hypertrophy, hypertension, heart disease. May affect ability to drive or operate machinery. Pregnancy and lactation.

Pregnancy-Lactation

Interactions

Increased BP with other sympathomimetic agents (e.g. decongestants, TCA, appetite suppressants). Reduced hypotensive effects of methyldopa, ?- and ?-adrenergic blockers. Increased side effects (e.g. somnolence, agitation) with atomoxetine. Potentially Fatal: Increased risk of hypertensive crisis with furazolidine, avoid concurrent use. Increased risk of hypertensive crisis with MAOIs; avoid concurrent use or within 2 wk after stopping MAOIs. Increased risk of psychosis with bromocriptine.

Adverse Effects

Side effects of Pseudoephedrine + Triprolidine : Dry mouth, nose and throat; skin rashes, tachycardia, drowsiness, sleep disturbances, urinary retention. Rarely, hallucinations.

Mechanism of Action

Triprolidine hydrochloride is a potent competitive histamine H1-receptor antagonist with antimuscarinic and mild sedative properties. Pseudoephedrine, an alpha- and beta-adrenergic receptor agonist, mediates vasoconstriction via direct stimulation of alpha-adrenergic receptors of the respiratory mucosa.

Note

Unifed "30mg, 1.25mg/5ml" Syrup manufactured by THE UNITED PHARMACEUTICAL MANUFACTURING CO. LTD.. Its generic name is Pseudoephedrine + Triprolidine. Unifed is availble in United Arab Emirates. Farmaco UAE drug index information on Unifed Syrup is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Pseudoephedrine + Triprolidine :

Syrup (Alcohol-free)
Tripofed 30mg/1.25mg per 5ml
Kuwait Saudi Pharmaceutical Industries Co. (KSPICO)
Syrup
Trifed "30mg, 1.25mg/5ml"
Al Hikma Pharmaceuticals
Tablets
Trifed "60mg, 2.5mgTablet"
Al Hikma Pharmaceuticals
Tablets
Sedofan "60mg, 2.5mg"
Julphar (Gulf Pharmaceutical Industries)
Syrup
Sedofan "30mg, 1.25mg/5ml"
Julphar (Gulf Pharmaceutical Industries)