Vancor Tablets / Film-coated

Pefloxacin
400mg
AL RAZI PHARMACEUTICAL INDUSTRIES CO. PLC
Pack size 10's Blister
Dispensing mode POM
Source JORDAN
AgentBALSAM DRUG STORE & MEDICAL EQUIPMENT
Retail Price 36.50 AED

Indications

Vancor Tablets / Film-coated is used for: Susceptible infections, Gonococcal urethritis, Acute uncomplicated cystitis

Adult Dose

Oral Susceptible infections Adult: 400 mg bid. Acute uncomplicated cystitis in women; Gonococcal urethritis in men Adult: 800 mg as single dose. IV Influsion Adult: 400 mg in 100 or 250 ml of 5% dextrose slow infusion over an hour bid.

Child Dose

Renal Dose

Renal impairment: Dose reduction may be necessary.

Administration

Should be taken with food. Take w/ meals.

Contra Indications

Hypersensitivity to quinolones, children <12 yr, pregnancy, lactation.

Precautions

Underlying CNS disease; hepatic disease; renal impairment. Avoid sun exposure, may cause severe sunburn.

Pregnancy-Lactation

Interactions

Reduced absorption with antacids, didanosine (DDI), iron salts, pirenzepine, sucralfate, vincristine, zinc salts; increased levels with cimetidine, probenecid, theophylline; increases the levels of cyclosporine; causes seizures with foscarnet, NSAIDs, piroxicam; hypoglycemia with glimeperide; antagonistic with quercetin.

Adverse Effects

Side effects of Pefloxacin : Nausea, vomiting, gastric pain, dizziness, insomnia, allergic skin reactions, thrombocytopaenia, leukopenia/neutropenia, photosensitisation, arthropathy, muscular pain, headache, delusions, depression, hallucinations, hepatic dysfunction.

Mechanism of Action

Pefloxacin is a fluoroquinolone antibacterial that exhibits its bactericidal action by inhibition of DNA gyrase and topoisomerase IV which are needed for bacterial DNA reproduction.

Note

Vancor 400mg Tablets / Film-coated manufactured by AL RAZI PHARMACEUTICAL INDUSTRIES CO. PLC. Its generic name is Pefloxacin. Vancor is availble in United Arab Emirates. Farmaco UAE drug index information on Vancor Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

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