Vancor Tablets / Film-coated
Pefloxacin
400mg
AL RAZI PHARMACEUTICAL INDUSTRIES CO. PLC
Pack size | 10's Blister |
---|---|
Dispensing mode | POM |
Source | JORDAN |
Agent | BALSAM DRUG STORE & MEDICAL EQUIPMENT |
Retail Price | 36.50 AED |
Indications
Vancor Tablets / Film-coated is used for:
Susceptible infections, Gonococcal urethritis, Acute uncomplicated cystitis
Adult Dose
Oral
Susceptible infections
Adult: 400 mg bid.
Acute uncomplicated cystitis in women; Gonococcal urethritis in men
Adult: 800 mg as single dose.
IV Influsion
Adult: 400 mg in 100 or 250 ml of 5% dextrose slow infusion over an hour bid.
Child Dose
Renal Dose
Renal impairment: Dose reduction may be necessary.
Administration
Should be taken with food. Take w/ meals.
Contra Indications
Hypersensitivity to quinolones, children <12 yr, pregnancy, lactation.
Precautions
Underlying CNS disease; hepatic disease; renal impairment. Avoid sun exposure, may cause severe sunburn.
Pregnancy-Lactation
Interactions
Reduced absorption with antacids, didanosine (DDI), iron salts, pirenzepine, sucralfate, vincristine, zinc salts; increased levels with cimetidine, probenecid, theophylline; increases the levels of cyclosporine; causes seizures with foscarnet, NSAIDs, piroxicam; hypoglycemia with glimeperide; antagonistic with quercetin.
Adverse Effects
Side effects of Pefloxacin :
Nausea, vomiting, gastric pain, dizziness, insomnia, allergic skin reactions, thrombocytopaenia, leukopenia/neutropenia, photosensitisation, arthropathy, muscular pain, headache, delusions, depression, hallucinations, hepatic dysfunction.
Mechanism of Action
Pefloxacin is a fluoroquinolone antibacterial that exhibits its bactericidal action by inhibition of DNA gyrase and topoisomerase IV which are needed for bacterial DNA reproduction.
Note
Vancor 400mg Tablets / Film-coated manufactured by AL RAZI PHARMACEUTICAL INDUSTRIES CO. PLC. Its generic name is Pefloxacin. Vancor is availble in United Arab Emirates.
Farmaco UAE drug index information on Vancor Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.