ZARZIO Injection
Recombinant filgrastim
48 IU/0.5ml
Sandoz GmbH
| Pack size | 0.5ml Pre-filled Syringe x 5 |
|---|---|
| Dispensing mode | POM |
| Source | AUSTRIA |
| Agent | ALPHAMED DRUG STORE |
| Retail Price | 2477.00 AED |
Available as:
Indications
ZARZIO Injection is used for:
Filgrastim is used in patients with acute myeloid leukemia receiving induction or consolidation chemotherapy. It is also used in cancer patients receiving bone marrow transplant. In general, filgrastim increases neutrophil counts in order to decrease the risk of infection or duration of neutropenia in the aforementioned patient populations. Infection and neutropenia are adverse events associated with chemotherapy. Furthermore, filgrastim is also indicated for patients with severe chronic neutropenia. It mobilizes hematopoietic progenitor cells into the peripheral blood for collection by leukapheresis to allow for a more rapid engraftment. Tbo-filgrastim has a narrower indication profile than neupogen - it is a leukocyte growth factor indicated for the reduction in the duration of severe neutropenia in patients with non-myeloid malignancies
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Recombinant filgrastim :
Mechanism of Action
Filgrastim binds to the g-csf receptor and stimulates the production of neutrophils in the bone marrow. As a g-csf analog, it controls proliferation of committed progenitor cells and influences their maturation into mature neutrophils. Filgrastim also stimulates the release of neutrophils from bone marrow storage pools and reduces their maturation time. Filgrastim acts to increase the phagocytic activity of mature neutrophils. In patients receiving cytotoxic chemotherapy, filgrastim can accelerate neutrophil recovery, leading to a reduction in duration of the neutropenic phase
Note
ZARZIO 48 IU/0.5ml Injection manufactured by Sandoz GmbH. Its generic name is Recombinant filgrastim. ZARZIO is availble in United Arab Emirates.
Farmaco UAE drug index information on ZARZIO Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.