Zerbaxa Injection
Ceftolozane (as sulfate), Tazobactam (as sodium)
"1147mg, 537mg"
MERCK CANADA INC.
| Pack size | 10 Vials |
|---|---|
| Dispensing mode | POM |
| Source | CANADA |
| Agent | CITY MEDICAL STORE |
| Retail Price | 4838.50 AED |
Indications
Zerbaxa Injection is used for:
CEFTOLOZANE
-Complicated Intra-abdominal Infections, used in combination with metronidazole. -Complicated Urinary Tract Infections, including Pyelonephritis.
TAZOBACTAM
Used in combination with piperacillin to broaden the spectrum of piperacillin antibacterial action.
-Complicated Intra-abdominal Infections, used in combination with metronidazole. -Complicated Urinary Tract Infections, including Pyelonephritis.
TAZOBACTAM
Used in combination with piperacillin to broaden the spectrum of piperacillin antibacterial action.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Ceftolozane (as sulfate), Tazobactam (as sodium) :
Mechanism of Action
CEFTOLOZANE
Ceftolozane belongs to the cephalosporin class of antibacterial drugs. The bactericidal action of ceftolozane results from inhibition of cell wall biosynthesis, and is mediated through binding to penicillin-binding proteins (PBPs). Ceftolozane is an inhibitor of PBPs of P. aeruginosa (e.g., PBP1b, PBP1c, and PBP3) and E. coli (e.g., PBP3).
TAZOBACTAM
Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
Ceftolozane belongs to the cephalosporin class of antibacterial drugs. The bactericidal action of ceftolozane results from inhibition of cell wall biosynthesis, and is mediated through binding to penicillin-binding proteins (PBPs). Ceftolozane is an inhibitor of PBPs of P. aeruginosa (e.g., PBP1b, PBP1c, and PBP3) and E. coli (e.g., PBP3).
TAZOBACTAM
Tazobactam broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.
Note
Zerbaxa "1147mg, 537mg" Injection manufactured by MERCK CANADA INC.. Its generic name is Ceftolozane (as sulfate), Tazobactam (as sodium). Zerbaxa is availble in United Arab Emirates.
Farmaco UAE drug index information on Zerbaxa Injection is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.