Zetop Tablets / Film-coated

Cetirizine Dihydrochloride
10mg
CADILA PHARMACEUTICALS LIMITED
Pack size 10's Blister
Dispensing mode POM
Source INDIA
AgentDUPHARM
Retail Price 15.50 AED

Indications

Zetop Tablets / Film-coated is used for: Allergic rhinitis, Hay fever, Urticaria, Allergies

Adult Dose

Oral: Allergic conditions Adult: 10 mg once daily or 5 mg b.i.d. Elderly: Initially, 5 mg once daily. Hepatic impairment: Initially, 5 mg once daily. Syrup: Adults: 2 teaspoon once daily or 1 teaspoon twice daily.

Child Dose

Oral Allergic conditions Child: 6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth; 2-5 yr 5 mg once daily or in 2 divided doses; >6 yr 10 mg once daily or in 2 divided doses. Syrup: Children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily. Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily. <2 years: Safety and efficacy not established

Renal Dose

Renal impairment GFR >50 mL/min: Dose adjustment not necessary GFR ? 50 mL/min: 5 mg PO qDay Peritoneal dialysis: 5 mg PO qDay Intermittent hemodialysis: 5 mg PO qDay; may also administer 3 times weekly

Administration

Can be taken with or without food.

Contra Indications

Lactation, Hypersensitivity

Precautions

Hepatic or renal impairment; Elderly; Pregnancy; Lactation: Excreted in breast milk; use not recommended; Tasks requiring mental alertness eg, driving or operating heavy machinery;

Pregnancy-Lactation

Pregnancy There are no adequate and well-controlled studies in pregnant women Lactation Cetirizine has been reported to be present in human breast milk In mice and beagle dogs, studies indicated that cetirizine was excreted in milk When a drug is present in animal milk, it is likely it will be present in human milk

Interactions

Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).

Adverse Effects

Side effects of Cetirizine Dihydrochloride : >10% Somnolence (2-14%), Headache (11-14%) 1-10% Fatigue (5.9%), Dry mouth (5%), Dizziness (2%), Diarrhea (2-3%), Malaise (4%), Bronchospasm (2-3%), Vomiting (2-3%), Epistaxis (2-4%) <1% Stomach pain, Drowsiness, Angioedema, Fussiness, Hallucinations, Hypotension, Tremor, Tongue discoloration

Mechanism of Action

Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.

Note

Zetop 10mg Tablets / Film-coated manufactured by CADILA PHARMACEUTICALS LIMITED. Its generic name is Cetirizine Dihydrochloride. Zetop is availble in United Arab Emirates. Farmaco UAE drug index information on Zetop Tablets / Film-coated is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.

Some other brands of Cetirizine Dihydrochloride :