Zyrtec Drops (Oral)
Cetirizine Dihydrochloride
10mg/ml
UCB PHARMA S.p.A.
| Pack size | 10ml Bottle |
|---|---|
| Dispensing mode | POM |
| Source | ITALY |
| Agent | Modern Pharmaceutical Co. |
| Retail Price | 22.00 AED |
Available as:
Indications
Zyrtec Drops (Oral) is used for:
Allergic rhinitis,
Hay fever,
Urticaria,
Allergies
Adult Dose
Oral:
Allergic conditions
Adult: 10 mg once daily or 5 mg b.i.d.
Elderly: Initially, 5 mg once daily.
Hepatic impairment: Initially, 5 mg once daily.
Syrup:
Adults: 2 teaspoon once daily or 1 teaspoon twice daily.
Child Dose
Oral
Allergic conditions
Child:
6-23 mth 2.5 mg once daily increased to max of 2.5 mg bid in childn >12 mth;
2-5 yr 5 mg once daily or in 2 divided doses;
>6 yr 10 mg once daily or in 2 divided doses.
Syrup:
Children over 6 years: 2 teaspoon once daily or 1 teaspoon twice daily.
Children 2-6 years: 1 teaspoonful once daily or 1/2 teaspoon twice daily.
<2 years: Safety and efficacy not established
Renal Dose
Renal impairment
GFR >50 mL/min: Dose adjustment not necessary
GFR ? 50 mL/min: 5 mg PO qDay
Peritoneal dialysis: 5 mg PO qDay
Intermittent hemodialysis: 5 mg PO qDay; may also administer 3 times weekly
Administration
Can be taken with or without food.
Contra Indications
Lactation,
Hypersensitivity
Precautions
Hepatic or renal impairment;
Elderly;
Pregnancy;
Lactation: Excreted in breast milk; use not recommended;
Tasks requiring mental alertness eg, driving or operating heavy machinery;
Pregnancy-Lactation
Pregnancy
There are no adequate and well-controlled studies in pregnant women
Lactation
Cetirizine has been reported to be present in human breast milk
In mice and beagle dogs, studies indicated that cetirizine was excreted in milk
When a drug is present in animal milk, it is likely it will be present in human milk
Interactions
Additive CNS depression when administered concomitantly w/ other CNS depressants (e.g. sedatives, tranquilisers).
Adverse Effects
Side effects of Cetirizine Dihydrochloride :
>10%
Somnolence (2-14%), Headache (11-14%)
1-10%
Fatigue (5.9%), Dry mouth (5%), Dizziness (2%), Diarrhea (2-3%), Malaise (4%), Bronchospasm (2-3%), Vomiting (2-3%), Epistaxis (2-4%)
<1%
Stomach pain, Drowsiness, Angioedema, Fussiness, Hallucinations, Hypotension, Tremor, Tongue discoloration
Mechanism of Action
Cetirizine is a potent and highly selective antagonist of the peripheral histamine H1-receptor on effector cells in the GI tract, blood vessels and resp tract.
Note
Zyrtec 10mg/ml Drops (Oral) manufactured by UCB PHARMA S.p.A.. Its generic name is Cetirizine Dihydrochloride. Zyrtec is availble in United Arab Emirates.
Farmaco UAE drug index information on Zyrtec Drops (Oral) is not intended for diagnosis, medical advice or treatment; neither intended to be a substitute for the exercise of professional judgment.
Some other brands of Cetirizine Dihydrochloride :
Solution (Oral)
Zyrtec
1mg/ml
UCB PHARMA S.p.A.
Tablets / Film-coated
Zyrtec
10mg
UCB FARCHIM SA
Tablets / Film-coated
Zyrtec
10mg
UCB FARCHIM SA
Tablets / Film-coated
Zetop
10mg
CADILA PHARMACEUTICALS LIMITED
Tablets / Film-coated
Zertazine
10mg
Riyadh Pharma (Medical and Cosmetic Products Company Ltd.)