Adapalene 0.3% Topical
Adapalene 0.3% Topical is used for: Acne
Adult: Topical As 0.3% soln/cream/gel: Apply once daily at night.
Patients with sunburn, eczema. Pregnancy, lactation. Avoid excessive exposure to sunlight or UV irradiation. Keep away from the eyes, lips, nostrils and mucous membranes. Do not apply to cuts, abrasions, scaly or flaky skin, or patches of sunburned skin. Use with caution with preparations containing sulfur, resorcinol, or salicylic acid.
Pregnancy category: C Lactation: Excretion in milk unknown; use with caution
Increased irritation may occur with medicated or abrasive soaps, products with a pronounced drying effect and those containing alcohol or astringents.
Side effects of Adapalene 0.3% Topical : Mild skin irritation, scaling, erythema, cutaneous dryness, sensations of stinging and burning, pruritus.
Mechanism of Action
Adapalene binds to specific retinoic acid nuclear receptors which normalises the differentiation of follicular epithelial cells resulting in decreased microcomedone formation.