Adrenochrome Monosemicarbazone
Indications
Adrenochrome Monosemicarbazone is used for:
Capillary bleeding, Haemoptysis, Haematuria, Retinal hemorrhage,Se condary hemorrhage, Menorrhagia.
Adult Dose
Oral As a haemostatic
Adult: 10-30 mg tid.
Injection As a haemostatic Adult: 10 mg daily by SC/IM inj.
Alternatively, 25-100 mg daily by IV Inj or drip infusion.
Pre-operative: 2-6ml at suitable intervals.
Post-operative: 1-2ml every 2hrs.
Non-surgical: 2-4ml tid.
Child Dose
Child <6yrs: 1-2ml tid.
Renal Dose
Administration
Contra Indications
Should not be administered to patients with hypersensitivity.
Precautions
Because of the content of diprophylline (90 mg/ml), the dosage to premature babies, infants and young children should not exceed 0.3 ml.
Pregnancy-Lactation
Interactions
No specific drug interaction has been demonstrated.
Adverse Effects
Side effects of Adrenochrome Monosemicarbazone :
Allergic reactions may occur like dyspnoea, bronchospasm, skin reaction etc
Mechanism of Action
Carbazochrome is an oxidation product of adrenaline (epinephrine). It has been used as a haemostatic agent.