Amorolfine topical
Indications
Amorolfine topical is used for:
Tinea Pedis, Tinea cruris, Tinea corporis, Tinea manuum, Tinea anguinalis, Tinea versicolor
Adult Dose
Topical
Skin fungal infections
Topical/Cutaneous
Skin fungal infections
Adult: As 0.25% cream: Apply once daily for at least 2-3 weeks (up to 6 weeks for foot infections). Continue for 3-5 days after cure is attained.
Child Dose
Renal Dose
Administration
Applied on the affected areas once daily in the evening for 2 to 3 weeks
Continued for 3 to 5 days after clinical cure is fully achieved.
Contra Indications
Precautions
Children. Pregnancy and lactation.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Amorolfine topical :
Hypersensitivity reactions, skin irritation, erythema, pruritus, contact dermatitis, urticaria, blister. Rarely, burning sensation, severe skin reactions, nail disorder (e.g. nail discolouration, onychoclasis, onychorrhexis)
Mechanism of Action
Amorolfine, a morpholine derivative, is highly active in vitro against numerous pathogenic and opportunistic fungi. It alters fungal cell membranes by interfering w/ sterol biosynthesis.