Anhydrous Glucose + Citric Acid + Potassium Chloride

Indications

Anhydrous Glucose + Citric Acid + Potassium Chloride is used for: Diarrhea, Gastro-enteritis with dehydration

Adult Dose

For oral administration only. Reconstitution: The powder contents of one sachet or two effervescent tablets should be made up to 200ml with fresh drinking water. (For infants, the water should be freshly boiled and cooled before mixing with Gastrolyte Electrolyte Rehydration Formula). An infant's feeding bottle is a convenient measure of this volume. The solution should be made up immediately prior to feeding and any solution remaining an hour after reconstitution should be discarded. However, the solution may be used for up to 24 hours if stored in a refrigerator immediately after reconstitution. The reconstituted solution must not be boiled.

Child Dose

Renal Dose

Administration

Contra Indications

There are no known contraindications to Gastrolyte Electrolyte Rehydration Formula. However, there may be a number of conditions where treatment with Gastrolyte Electrolyte Rehydration Formula will be inappropriate, e.g. intestinal obstruction requiring surgical intervention.

Precautions

Use water ONLY to mix Gastrolyte Electrolyte Rehydration Formula powder or effervescent tablets. Never dilute with lemonade, soft drinks, cordials or any other fluid than water. Gastrolyte Electrolyte Rehydration Formula powder is available with either sodium saccharin or aspartame as a sweetening agent. Phenylketonurics are warned that this product, in some forms, contains phenylalanine. Please refer to the packaging for information relating to the sweetening agent used. For oral administration only. The contents of one sachet or two effervescent tablets should always be made up to 200ml with water (the product must not be reconstituted in diluents other than water, e.g. must not be included in milk solutions). A weaker solution than recommended will fail to provide adequate sugar and electrolytes and a stronger solution than recommended may give rise to hypernatraemia. Intravenous rehydration is required for dehydrated children with shock, very large stool losses (>10mL/kg/hour), severe vomiting that interferes with oral fluid replacement, or glucose malabsorption. Patients with gastroenteritis should be monitored carefully to ensure that their condition does not deteriorate. In particular, young infants may become severely dehydrated in a short time. Patients and/or parents should be advised to seek medical advice if the condition worsens. Clinicians should particularly ensure patients are aware of the risk of dehydration in young children and infants. Early warning signs of impending dehydration should be discussed. Seek medical advice if diarrhoea persists for more than 6 hours in infants under 6 months, 12 hours in children aged 6 months to 3 years, 24 hours in children aged 3 to 6 years and 48 hours in children over 6 years of age.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Anhydrous Glucose + Citric Acid + Potassium Chloride : None reported.

Mechanism of Action

Glucose is the end product of carbohydrate metabolism and is the chief source of energy for all cellular activities. Potassium chloride is a major cation of the intracellular fluid. It plays an active role in the conduction of nerve impulses in the heart, brain and skeletal muscle; contraction of cardiac skeletal and smooth muscles; maintenance of normal renal function, acid-base balance, carbohydrate metabolism and gastric secretion. Potassium citrate is absorbed and metabolized to potassium bicarbonate and this acts as a systemic alkalizer .