Antazoline phosphate, Naphazoline HCl
Indications
Antazoline phosphate, Naphazoline HCl is used for:
ANTAZOLINE
Used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis
NAPHAZOLINE
Naphazoline is primarily indicated in conditions like corneal vascularity, hyperaemia, itching, nasal congestion, and can also be given in adjunctive therapy as an alternative drug of choice in sinusitis
Used to relieve nasal congestion and in eye drops, usually in combination with naphazoline, to relieve the symptoms of allergic conjunctivitis
NAPHAZOLINE
Naphazoline is primarily indicated in conditions like corneal vascularity, hyperaemia, itching, nasal congestion, and can also be given in adjunctive therapy as an alternative drug of choice in sinusitis
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Antazoline phosphate, Naphazoline HCl :
Mechanism of Action
ANTAZOLINE
Antazoline binds to the histamine h1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine
NAPHAZOLINE
Naphazoline is a direct acting sympathomimetic drug, which acts on alpha-adrenergic receptors in the arterioles of the nasal mucosa. This activates the adrenal system to yield systemic vasoconstrction. In producing vasoconstriction, the result is a decrease in blood flow in the nasal passages and consequently decreased nasal congestion. The vasoconstriction means that there is less pressure in the capillaries and less water can filter out, thus less discharge is made
Antazoline binds to the histamine h1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms brought on by histamine
NAPHAZOLINE
Naphazoline is a direct acting sympathomimetic drug, which acts on alpha-adrenergic receptors in the arterioles of the nasal mucosa. This activates the adrenal system to yield systemic vasoconstrction. In producing vasoconstriction, the result is a decrease in blood flow in the nasal passages and consequently decreased nasal congestion. The vasoconstriction means that there is less pressure in the capillaries and less water can filter out, thus less discharge is made