Antipyrine, Benzocaine, Hexylresorcinol, Tyrothricin

Indications

Antipyrine, Benzocaine, Hexylresorcinol, Tyrothricin is used for: ANTIPYRINE
Antipyrine is an analgesic often used to test effects of other drugs on liver enzymes
BENZOCAINE
For general use as a lubricant and topical anesthetic on esophagus, larynx, mouth, nasal cavity, rectum, respiratory tract or trachea, urinary tract, vagina. It is also used to suppress gag reflex

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Antipyrine, Benzocaine, Hexylresorcinol, Tyrothricin :

Mechanism of Action

ANTIPYRINE
Antipyrine is thought to act primarily in the cns, increasing the pain threshold by inhibiting both isoforms of cyclooxygenase, cox-1, cox-2, and cox-3 enzymes involved in prostaglandin (pg) synthesis
BENZOCAINE
Benzocaine binds to sodium channels and reversibly stabilizes the neuronal membrane which decreases its permeability to sodium ions. Depolarization of the neuronal membrane is inhibited thereby blocking the initiation and conduction of nerve impulses