Benzoyl Peroxide 4%

Indications

Benzoyl Peroxide 4% is used for: Acne vulgaris

Adult Dose

Adult: Topical Acne cream: Apply 1-2 times/day.

Child Dose

Renal Dose

Administration

Apply sparingly to affected areas after thoroughly washing skin.

Contra Indications

Hypersensitivity.

Precautions

Discontinue if severe irritation develops. Restart with tolerable levels of treatment after irritiation has cleared. Do not use occlusive dressing. May cause dermatitis in allergic patients. Apply carefully near the eyes, mouth, neck and other mucous membranes as well as other sensitive areas.

Pregnancy-Lactation

Pregnancy Category: C Lactation: excretion in milk unknown; use with caution

Interactions

PABA sunscreens may transiently discolour fabric.

Adverse Effects

Side effects of Benzoyl Peroxide 4% : Excessive drying of skin, allergic dermatitis. May bleach fabrics or hair. Skin discoloration; skin rash, peeling, transient local oedema.

Mechanism of Action

Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its oxidative property. It is active against S.epidermidis and P.acne.