Benzoyl Peroxide 4%
Indications
Benzoyl Peroxide 4% is used for:
Acne vulgaris
Adult Dose
Adult: Topical Acne cream: Apply 1-2 times/day.
Child Dose
Renal Dose
Administration
Apply sparingly to affected areas after thoroughly washing skin.
Contra Indications
Hypersensitivity.
Precautions
Discontinue if severe irritation develops. Restart with tolerable levels of treatment after irritiation has cleared. Do not use occlusive dressing. May cause dermatitis in allergic patients. Apply carefully near the eyes, mouth, neck and other mucous membranes as well as other sensitive areas.
Pregnancy-Lactation
Pregnancy Category: C
Lactation: excretion in milk unknown; use with caution
Interactions
PABA sunscreens may transiently discolour fabric.
Adverse Effects
Side effects of Benzoyl Peroxide 4% :
Excessive drying of skin, allergic dermatitis. May bleach fabrics or hair. Skin discoloration; skin rash, peeling, transient local oedema.
Mechanism of Action
Benzoyl peroxide has mild keratolytic effect and antimicrobial activity which is attributed to its oxidative property. It is active against S.epidermidis and P.acne.