Bimatoprost 0.03% + Timolol 0.5% eye prep

Indications

Bimatoprost 0.03% + Timolol 0.5% eye prep is used for: Reduction of intra-ocular pressure in adult patients with, open-angle glaucoma, ocular hypertension

Adult Dose

Adult: Eye drop: The recommended dose is one drop in the affected eye(s) once-daily.

Child Dose

Safety and effectiveness in pediatric patients have not been established.

Renal Dose

Administration

Contra Indications

It is contraindicated in patients with known hypersensitivity to any ingredient of this formulation.

Precautions

The active substances Timolol/ Bimatoprost may be absorbed systemically. Due to the beta-adrenergic component, Timolol, the same types of cardiovascular, pulmonary and other adverse reactions as seen with systemic beta-blockers may occur. Caution should be exercised in treating patients with severe or unstable and uncontrolled cardiovascular Disease.

Pregnancy-Lactation

Interactions

There is a potential for bradycardia when ophthalmic beta-blockers solution is administered concomitantly with oral calcium channel blockers, guanethidine, beta-adrenergic blocking agents, parasympathomimetics, anti-arrhythmic and digitalis glycosides. Concomitant ocular medications should be administered at least 5 min apart from the instillation of this Eye Drops.

Adverse Effects

Side effects of Bimatoprost 0.03% + Timolol 0.5% eye prep : 26% Ocular hyperemia 5-10% Decreased visual acuity, eye discomfort, foreign body sensation, pain and pruritis

Mechanism of Action