Calcipotriol
Indications
Calcipotriol is used for:
Plaque psoriasis, Scalp psoriasis, Alopecia areata
Adult Dose
Adult: Topical Plaque psoriasis As cream/oint: Apply 1-2 times/day.
Max: 100 g per wk.
Scalp psoriasis As soln: Apply 1-2 times/day.
Max: 60 mL per week.
Child Dose
Topical/Cutaneous
Mild to moderate plaque psoriasis
Child: Apply cream/ointment 2 times daily.
Max: >12 yr: 75 g/wk; 6-12 yr: 50 g/week.
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Not to be applied on the face; pregnancy and lactation.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Calcipotriol :
Skin irritation, erythema, scaling; hypercalcemia w/ high doses.
Mechanism of Action
Calcipotriol is a derivative of vitamin D3. It has the property of inducing differentiation and suppression of keratinocytes.