Carbonyl Iron
Indications
Carbonyl Iron is used for:
Dietary supplement, Iron deficiencies, Iron deficiency anemia
Adult Dose
One capsule daily. In more severe cases, 2 capsules a day may be required
Child Dose
>12 years old: Same as adult
Severe Iron Deficiency Anemia
4-6 mg/kg PO divided q8hr
Mild to Moderate Iron Deficiency Anemia
3 mg/kg PO qDay or divided q12hr
Prophylaxis
1-2 mg/kg PO; 15 mg PO maximum
Renal Dose
Administration
For maximum absorption take on empty stomach, but may take with or after meals to minimize GI irritation
Contra Indications
This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.
Precautions
Care should be taken in patients who may develop iron overload, such as those with haemochromatosis, haemolytic anaemia or red cell aplasia. Iron chelates with tetracycline and absorption may be impaired.
Lactation: Excreted in breast milk
Pregnancy-Lactation
Pregnancy Category: Not available
Lactation: Excreted in breast milk
Interactions
Antacids may decrease the absorption of carbonyl iron.
Adverse Effects
Side effects of Carbonyl Iron :
>10%
Constipation, Diarrhea, Nausea, Epigastric pain, Dark stools, Vomiting
Frequency Not Defined
Hemosiderosis (during long-term administration of large amounts), Urine discoloration, Dental stain by some formulations, Heartburn
Mechanism of Action
Iron: Essential component in the formation of hemoglobin; adequate amounts of iron are necessary for effective erythropoiesis; also serves as a cofactor of several essential enzymes, including cytochromes that are involved in electron transport. Replacement of iron stores found in hemoglobin, myoglobin, and enzymes; works to transport oxygen via hemoglobin.