Cetirizine eye prep
Indications
Cetirizine eye prep is used for:
Allergic conjunctivitis
Adult Dose
Allergic Conjunctivitis
Indicated for ocular itching associated with allergic conjunctivitis
Instill 1 drop in each affected eye BID (~8 hr apart)
Child Dose
Allergic Conjunctivitis
Indicated for ocular itching associated with allergic conjunctivitis
<2 years: Safety and efficacy not established
>2 years: Instill 1 drop in each affected eye BID (~8 hr apart)
Renal Dose
Administration
Contra Indications
Precautions
Care should be taken not to touch the eyelids or surrounding areas with the dropper tip of the bottle to prevent contaminating the tip and solution; keep the bottle closed when not in use
Advise patient to not wear contact lenses if their eye is red
Do not instill drops while wearing contact lenses; remove contacts before instillation; may be reinserted 10 minutes after administration; benzalkonium chloride (preservative) may be absorbed by soft contact lenses
Not for treatment of contact lens-related irritation
Pregnancy-Lactation
Pregnancy
No adequate or well-controlled studies of cetirizine ophthalmic in pregnant women
Use in pregnancy only if potential benefit justifies potential risk to fetus
Lactation
Unknown if ophthalmic cetirizine distributed in human breast milk; orally administered cetirizine is excreted in human breast milk
Consider the developmental and health benefits of breastfeeding along with the mother’s clinical need for the drug, and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition
Interactions
Adverse Effects
Side effects of Cetirizine eye prep :
1-10%
Hyperemia (1-7%)
Instillation site pain (1-7%)
Reduced visual acuity (1-7%)
Mechanism of Action
Histamine-1 receptor antagonist; inhibits histamine release from mast cells, decreases chemotaxis, and inhibits eosinophil activation