Chlorhexidine Gluconate 1 % Oral prep
Indications
Chlorhexidine Gluconate 1 % Oral prep is used for:
Dental and gum infection.
Adult Dose
Adult: As cream/gel: Apply to the affected area 2-3 times daily or as directed by physician.
Child Dose
Renal Dose
Administration
Contra Indications
Hypersensitivity.
Precautions
Avoid eating, drinking, or brushing your teeth just after using this medicationAvoid contact w/ eyes. Do not inject or use in body cavities.
Pregnancy-Lactation
Interactions
Soaps, other anionic agents, borates, bicarbonates, carbonates, chlorides, citrates, nitrates, phosphates & sulfates.
Adverse Effects
Side effects of Chlorhexidine Gluconate 1 % Oral prep :
Local irritation. Chlorhexidine gluconate can stain teeth, dentures, tooth restorations, your tongue, or the inside of your mouth.
Mechanism of Action
Chlorhexidine is a very potent cationic chemoprophylactic agent that has a broad-spectrum of activity against gm+ve and gm-ve bacteria. It is both bacteriostatic and bactericidal depending on its concentration. The bactericidal effect, which is achieved at high concentrations, is due to the binding of the cationic to negatively charged bacterial cell walls and extramicrobial complexes. Bacteriostatic effect is achieved at low concentrations which causes an alteration of bacterial cell osmotic equilibrium and leakage of potassium and phosphorus.