Chondroitin + Glucosamine

Indications

Chondroitin + Glucosamine is used for: Osteoarthritis, rheumatoid arthritis, sport injuries, migraine, different skin problems (e.g., psoriasis), vascular complications (e. g., atherosclerosis), kidney stones, and inflammatory bowel disease (e.g., ulcerative colitis, leaky gut syndrome), Nutritional supplement, Dietary supplement

Adult Dose

Adult Oral 1 to 2 tablets three times daily. Obese individuals may need higher doses, based on body weight. Typical dosage recommendation, based on body weight is as follows- Under 54 Kg: 800 mg Chondroitin Sulfate & 1000 mg Glucosamine Sulfate per day 54 Kg - 91 Kg: 1200 mg Chondroitin Sulfate & 1500 mg Glucosamine Sulfate per day Over 91 Kg: 1600 mg Chondroitin Sulfate & 2000 mg Glucosamine Sulfate per day

Child Dose

Renal Dose

Administration

Should be taken with food. Preferably taken at meals.

Contra Indications

Proven hypersensitivity (e. g. allergic to shellfish or sulfur) to Glucosamine and Chondroitin is a contraindication.

Precautions

Diabetic patients, patients on heparin. Pregnancy and lactation. Lactation: Unknown; not recommended

Pregnancy-Lactation

Pregnancy Category: Unknown; not recommended Lactation: Unknown; not recommended

Interactions

May increase insulin resistance & affect glucose tolerance; reduce antidiabetic agent effectiveness. Increase INR value w/ warfarin & potentiates anticoagulant effect.

Adverse Effects

Side effects of Chondroitin + Glucosamine : Chondroitin Sulfate: Allergic reactions, alopecia, constipation, diarrhea, edema, (eyelid/lower limb), epigastric pain, extrasystoles, nausea. Glucosamine Sulfate: Possible poor glycemic control in diabetics; monitor blood glucose, Increased intraocular pressure (see Cautions), Constipation, Diarrhea, Drowsiness, Headache, Heartburn, Hyperinsulinemia, Nausea, Skin reactions

Mechanism of Action

Glucosamine Sulphate: A special ingredient to help keep joints in good shape. Glucosamine is naturally required by the body for the production of collagen to cushion the joints (cartilage) and synovial fluid which bathes and lubricates them. It is present in the formulation in the preferred potassium form, with minerals for improved absorption. Glucosamine stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage. Chondroitin Sulphate: Helps form the proteins that maintain cartilage elasticity and works synergistically with glucosamine to help maintain joint health. Chondroitin is cartilage derivative; component of hyaline cartilage matrix that may repair cartilage & reduce synovial inflammation.