Cinchocaine HCI + Hydrocortisone + Framycetin Sulphate + Esculin (Rectal prep)

Indications

Cinchocaine HCI + Hydrocortisone + Framycetin Sulphate + Esculin (Rectal prep) is used for: Internal and external haemorrhoids, Haemorrhoids post-partum, Anal pruritus, peri-anal eczema, anal fissures, proctitis, Post-haemorrhoidectomy application to relieve pain and discomfort.

Adult Dose

Adult: Ointment Apply onto the affected area in the morning and evening and after each stool. Suppository Insert 1 suppository in the morning and evening and after each stool.

Child Dose

Renal Dose

Administration

Apply the ointment in small quantity with the finger, on the painful or pruritic area, morning and evening and after each stool. For deep application attach applicator/cannula (supplied) to tube, insert to full extent and squeeze tube gently from lower end whilst withdrawing.

Contra Indications

Application to inflamed or infected tissues or to damaged skin mucosa; instillation into the middle ear.

Precautions

Avoid application for prolonged periods and to extensive areas. Pregnancy, lactation.

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Cinchocaine HCI + Hydrocortisone + Framycetin Sulphate + Esculin (Rectal prep) : Restlessness; excitement; nervousness; paraesthesias; dizziness; tinnitus; blurred vision; nausea; vomiting; muscle twitching; tremors; convulsions; hypotension; bradycardia; arrhythmias; cardiac arrest.

Mechanism of Action

Cinchocaine prevents or diminishes nerve impulse conduction near to the site of admin. It also has membrane-stabilising effect owing to decrease of permeability of the nerve cell to sodium ions. Hydrocortisone is a corticosteroid used for its anti-inflammatory and immunosuppressive effects. Its anti-inflammatory action is due to the suppression of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It may also be used as replacement therapy in adrenocortical insufficiency. Framycetin Sulphatethe broad spectrum antibiotic,Framycetin Sulphate,eradicates most infections which may already be present or arise in lesions of the anorectal area. Esculin improves skin vasculature and is effective in the management of cellulitis.