Cinoxacin
Indications
Cinoxacin is used for:
For the treatment of initial and recurrent urinary tract infections in adults caused by the following susceptible microorganisms: escherichia coli, proteus mirabilis, proteus vulgaris, klebsiella species (including k. Pneumoniae), and enterobacter species
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Cinoxacin :
Mechanism of Action
Evidence exists that cinoxacin binds strongly, but reversibly, to dna, interfering with synthesis of rna and, consequently, with protein synthesis. It appears to also inhibit dna gyrase. This enzyme is necessary for proper replicated dna separation. By inhibiting this enzyme, dna replication and cell division is inhibited