Dequalinium Chloride vaginal prep

Indications

Dequalinium Chloride vaginal prep is used for: Treatment of, Bacterial vaginosis

Adult Dose

Vaginal Bacterial vaginosis Adult: Vaginal Tablet (VT) The recommended dose is 1 vaginal tablet (10mg) daily P/V for 6 days.

Child Dose

There is insufficient experience of the use of Dequalinium VT in children and adolescents under 18 years of age.

Renal Dose

Administration

Use every evening before bed. • Wash hands before opening the blister pack. • Lie down in a reclining position with the legs slightly bent. Insert one vaginal tablet deeply into the vagina. • Should stop the treatment during the heavy bleeding period of your menstruation and resume afterwards.

Contra Indications

Hypersensitivity to the active substance or to any of the excipients present in medication. Ulceration of the vaginal epithelium and the vaginal portion of the cervix. Those who have not yet had their first menstruation, and thus did not reach sexual maturity must not use it.

Precautions

Intravaginal use of soaps, spermicides and vaginal douches (vaginal washes) is not recommended during treatment with Dequalinium VT. Treatment should be stopped during the heavy bleeding period of menstruation and resume afterwards. As with all vaginal infections, unprotected sexual intercourse during treatment with Dequalinium VT is prohibited. To minimize exposure of the newborn to dequalinium chloride, vaginal tablets should not be used within 12 hours before birth.

Pregnancy-Lactation

Based on previous experience and since Dequalinium acts locally, no harmful effects on pregnancy and/or the unborn and breast fed infant are expected. Dequalinium VT should only be used during pregnancy and during breast-feeding if medically needed.

Interactions

Adverse Effects

Side effects of Dequalinium Chloride vaginal prep : Vaginal discharge, vaginal itching or vaginal burning, vaginal yeast infection, thrush. Can get worse at the beginning of the treatment, before they start to get better. Some other side effects - Vaginal bleeding, vaginal pain - Inflammation of vagina - Headache - Nausea

Mechanism of Action

Dequalinium is a bisquanternary quinolinium anti-infective agent against gram-positive and gram-negative bacteria, fungi, protozoa and yeast. It increases bacterial cell permeability and reduces enzymatic activity, thus causing cell death.