Dextrose 5% + Sodium Chloride 0.25%
Indications
Dextrose 5% + Sodium Chloride 0.25% is used for:
Parenteral nutrition, Dehydration, Fluid and Electrolytes imbalance
Adult Dose
Adult: IV Dose depends on age, wt and clinical condition of the patient.
Child Dose
Renal Dose
Administration
Contra Indications
Allergy to corn products.
Precautions
May cause fluid and/or solute overload. Caution when used in patients with CHF, severe renal impairment or clinical conditions whereby there is sodium retention with oedema. Monitor serum potassium levels. Not to be administered concurrently with blood through the same infusion set due to risk of agglomeration. Patients with overt or known subclinical DM, or carbohydrate intolerance. Risk of hypokalaemia during parenteral admin of hypertonic dextrose solutions. Paediatric patients especially neonates and very low birth weight infants. Caution when used in patients receiving corticosteroids or corticotropin. Pregnancy.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Dextrose 5% + Sodium Chloride 0.25% :
Fever, infection at the site of inj, venous thrombosis or phlebitis extending from the site of inj, extravasation and hypervolaemia.
Mechanism of Action
Dextrose and sodium chloride solutions are used as sources of electrolytes, calories and water for hydration. Sodium and chloride ions are responsible for regulating the acid-base balance of the body. Dextrose is a source of calories. It is readily metabolised and helps to decrease losses of body protein and nitrogen. It also promotes glycogen deposition and decreases or prevents ketosis.