Diphenhydramine, Dextromethorphan, Pseudoephedrine, Ammonium chloride, Sodium citrate, Menthol
Indications
Diphenhydramine, Dextromethorphan, Pseudoephedrine, Ammonium chloride, Sodium citrate, Menthol is used for:
DIPHENHYDRAMINE
For the treatment of symptoms associated with vertigo/meniere's disease, nausea and vomiting, motion sickness and insect bite
DEXTROMETHORPHAN
For treatment and relief of dry cough
For the treatment of symptoms associated with vertigo/meniere's disease, nausea and vomiting, motion sickness and insect bite
DEXTROMETHORPHAN
For treatment and relief of dry cough
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Diphenhydramine, Dextromethorphan, Pseudoephedrine, Ammonium chloride, Sodium citrate, Menthol :
Mechanism of Action
DIPHENHYDRAMINE
Diphenhydramine competes with free histamine for binding at ha-receptor sites. This antagonizes the effects of histamine on ha-receptors, leading to a reduction of the negative symptoms brought on by histamine ha-receptor binding
DEXTROMETHORPHAN
Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the nmda glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier. The first-pass through the hepatic portal vein results in some of the drug being metabolized into an active metabolite of dextromethorphan, dextrorphan, the 3-hydroxy derivative of dextromethorphan
Diphenhydramine competes with free histamine for binding at ha-receptor sites. This antagonizes the effects of histamine on ha-receptors, leading to a reduction of the negative symptoms brought on by histamine ha-receptor binding
DEXTROMETHORPHAN
Dextromethorphan is an opioid-like drug that binds to and acts as antagonist to the nmda glutamatergic receptor, it is an agonist to the opioid sigma 1 and sigma 2 receptors, it is also an alpha3/beta4 nicotinic receptor antagonist and targets the serotonin reuptake pump. Dextromethorphan is rapidly absorbed from the gastrointestinal tract, where it enters the bloodstream and crosses the blood-brain barrier. The first-pass through the hepatic portal vein results in some of the drug being metabolized into an active metabolite of dextromethorphan, dextrorphan, the 3-hydroxy derivative of dextromethorphan