Fluorometholone 0.1 % Eye prep
Indications
Fluorometholone 0.1 % Eye prep is used for:
Allergic and inflammatory conditions of the eye
Adult Dose
Adults:
Instill 1-2 drops into conjunctival sac 2-3 times daily.
Dose may be increased to 1 drop hourly during first 24-48 hr.
Child Dose
Children (above 2 years of age):
Instill 1-2 drops into conjunctival sac 2-3 times daily.
Dose may be increased to 1 drop hourly during first 24-48 hr.
Renal Dose
Administration
Contra Indications
Viral diseases of the cornea and conjunctiva, including epithelial herpes simplex keratitis (dendritic keratitis), Vaccinia and Varicella, mycobacterial eye infection, ocular fungal infections, untreated eye infections; hypersensitivity.
Precautions
Glaucoma (check intraocular pressure periodically), history of herpes simplex fungal or bacterial infections. Not to be used in mustard gas keratitis and Sjogren's keratoconjunctivitis. May cause corneal and scleral thinning which may lead to perforation in serious cases. Use of steroids after cataract surgery may prolong healing time and increase bleb formation. Pregnancy, lactation; children <2 yr.
Pregnancy-Lactation
Pregnancy Category: C
Lactation: Excretion in milk unknown; not recommended
Interactions
Adverse Effects
Side effects of Fluorometholone 0.1 % Eye prep :
Mild burning sensation, reversible increase in intra ocular pressure (IOP), reactive hyperemia/rebound effect, cataract & corneal defects, glaucoma, systemic effects (chronic use).
Mechanism of Action
Fluorometholone suppresses the migration of polymorphonuclear leukocytes and reversal of increased capillary permeability thus decreasing inflammation.