Folic Acid + Vitamin C + Vitamin D3
Indications
Folic Acid + Vitamin C + Vitamin D3 is used for:
Dental bleeding, Lactation, Vitamin C, Vitamin D, Folic acid Deficiency
Adult Dose
Oral
Adult: 1 tab once daily.
Child Dose
Renal Dose
Administration
Contra Indications
This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.
Precautions
Precautions should be exercised if hypersensitivity to any of its ingredients is manifested.
Pregnancy-Lactation
Interactions
Folic acid: Antiepileptics, oral contraceptives, anti-TB drugs, alcohol, aminopterin, methotrexate, pyrimethamine, trimethoprim and sulphonamides may result to decrease in serum folate contrations. Decreases serum phenytoin concentrations.
Vit C: Deferroxamine, hormonal contraceptives, flufenazine, warfarin, elemental iron, salicylates, warfarin, fluphenazine, disulfiram, mexiletine, vitamin B12.
Vit D3: Increased risk of hypercalcaemia if given with thiazide diuretics, calcium or phosphate. Antiepileptics (e.g. carbamazepine, phenobarbitone, phenytoin & primidone) may increase vitamin D requirements. Rifampicin & isoniazid may reduce efficacy of vitamin D. Corticosteroids may counteract the effect of vitamin D. Digoxin or any cardiac glycoside. Reduced absorption when taken with cholestyramine, colestipol, mineral oil, orlistat. Ketoconazole.
Adverse Effects
Side effects of Folic Acid + Vitamin C + Vitamin D3 :
This tablet is well tolerated. Vitamin C & Vitamin D are well tolerated and side-effects are very rare at the recommended dose. Allergic sensitization has been reported following oral administration of folic acid.
Mechanism of Action
Folic acid: Required for nucleoprotein synthesis and the maintenance of normal erythropoiesis; folic acid is converted in the liver and plasma to its metabolically active form, tetrahydrofolic acid, by dihydrofolate reductase; prevents neural tube defects in women of childbearing potential and higher doses required during pregnancy.
Vitamin C is necessary for collagen formation and tissue repair; plays a role in oxidation/reduction reactions as well as other metabolic pathways including synthesis of catecholamines, carnitine, and steroids; also plays a role in conversion of folic acid to folinic acid.
Vitamin D3 is a fat-soluble sterol. It is necessary for the regulation and regulation of calcium and phosphate homoeostasis and bone mineralisation. Vitamin D is also essential for healthy bones as it aids in Calcium absorption from the GI tract. In addition to this it stimulates bone formation. Clinical studies also show that Calcium and Vitamin D has synergistic effects on bone growth as well as in Osteoporosis and fracture prevention.