Framycetin sulfate (Dressing)
Indications
Framycetin sulfate (Dressing) is used for:
Wounds dressings,
Thermal: Light, and not too extensive, burns or scalds.
Traumatic: Lacerations, abrasions, bites, wounds, crash injuries.
Miscellaneous: Secondary infected skin condition, (eg, eczema, dermatitis, herpes zoster).
Adult Dose
Apply a single layer on the lesion & cover w/ a suitable dressing. For wounds w/ profuse exudate change the dressing once daily.
Child Dose
Renal Dose
Administration
Contra Indications
Known allergy to lanolin or framycetin, or where organisms are known to be resistant to framycetin.
Precautions
Allergy to Streptomyces-derived antibiotics. Large-scale burns.
Pregnancy-Lactation
Interactions
Co-admin of gramicidin with framycetin reduces the risk of selecting resistant bacteria.
Adverse Effects
Side effects of Framycetin sulfate (Dressing) :
Possible ototoxicity
Open wounds, large areas, renal impairment on prolonged use.
Mechanism of Action
Framycetin is an aminoglyoside antibiotic which is the major component of neomycin. Susceptible organisms include many gram-negative bacteria (but not Pseudomonas) and many strains of Staphylococcus. Used topically in the treatment of skin, eye and ear infections often in combination with steroids and other antimicrobials.