Fructose 10%
Indications
Fructose 10% is used for:
Carbohydrate nutrient in diabetic patients, Fluid replacement, Caloric feeding
Adult Dose
It should not exceed 0.5-1 g/kg body weight per hour.
The usual recommended flow rate for adult is 30-75 drops per minute infused intravenously.
Child Dose
Renal Dose
Administration
Contra Indications
Contraindicated in certain inborn errors of fructose metabolism, methyl alcohol poisoning, hyperuricemia, liver failure, and lactic acidosis.
Precautions
It should be given with caution to patients with impaired kidney function or severe liver damage. Infusion of fluid should be immediately discontinued if rigor arises for any reason during the process. Do not use if the solution is cloudy, contains particles, or after expiry date.
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Fructose 10% :
Intravenous administration may cause lactic acidosis and hyperuricemia. The rapid infusion results in facial flushing, abdominal pain and sweating.
Mechanism of Action
Hyperosmolar carbohydrate solutions have a direct effect on the GI tract wall, resulting in reduced GI smooth muscle contraction.