Glucosamine
Indications
Glucosamine is used for:
Rheumatoid arthritis, Osteoarthritis, Nutritional supplement, Low back pain, Acute gout, Degenerative joint disease
Adult Dose
Oral
Osteoarthritis; Rheumatoid arthritis
Adult: 500 mg 3-4 times daily.
Max Dosage: 1500 mg/day.
Child Dose
Renal Dose
Administration
Should be taken with food. Preferably taken at meals.
Contra Indications
Allergy to shellfish.
Precautions
Diabetic patients, patients on heparin. Pregnancy and lactation.
Pregnancy-Lactation
Pregnancy Category: N/A
Lactation: N/A
Interactions
Glucosamine: May reduce effect of antidiabetic agents, doxorubicin, etoposide, tenoposide. May enhance anticoagulant activity of warfarin.
Adverse Effects
Side effects of Glucosamine :
Possible poor glycemic control in diabetics; monitor blood glucose, Increased intraocular pressure, Constipation, Diarrhea, Drowsiness, Headache, Heartburn, Hyperinsulinemia, Nausea, Skin reactions
Mechanism of Action
Glucosamine stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage.