High Molecular Weight Sodium hyaluronate, Low Molecular Weight Sodium hyaluronate
Indications
High Molecular Weight Sodium hyaluronate, Low Molecular Weight Sodium hyaluronate is used for:
For increase of absorption and distribution of other injected drugs and for rehydration.
Adult Dose
Child Dose
Renal Dose
Administration
Contra Indications
Precautions
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of High Molecular Weight Sodium hyaluronate, Low Molecular Weight Sodium hyaluronate :
Mechanism of Action
Hyaluronidase is a spreading or diffusing substance. It increase the permeability of connective tissue through the hydrolysis of hyaluronic acid. Hyaluronidase hydrolyzes hyaluronic acid by splitting the glucosaminidic bond between C1 of the glucosamine moiety and C4 of glucuronic acid. This temporarily decreases the viscosity of the cellular cement and increases diffusion of injected fluids or of localized transudates or exudates, thus facilitating their absorption.