Inositol nicotinate
Indications
Inositol nicotinate is used for:
Adjunct treatment to, Hyperlipidemia, raynaud's disease, intermittent claudication. May use in, stasis ulcers, dysmenorrhea, dermatitis herpetiformis, alcoholism, diabetes, cancer prevention, hypertension.
Adult Dose
Lipid-lowering and improving conditions related to peripheral vascular insufficiency
Recommended dosage 1500 mg to 4 grams daily, in divided dosages of two to three times daily.
Child Dose
Renal Dose
Administration
Contra Indications
Contraindicated to children, early stage of stroke & people who have recently had a heart attack. It should not be used if anyone is allergic to one or any of its ingredients
Precautions
Cautions should be exercised in patients with angina not well controlled by medical treatment and decreased blood supply through the vessels of the brain (cerebrovascular insufficiency).
Pregnancy-Lactation
Interactions
Adverse Effects
Side effects of Inositol nicotinate :
The most common side effects are headache, rash, paraesthesia, dizziness, nausea and vomiting, flushing, excessive fluid retention in the body tissues, postural hypotension, fainting
Mechanism of Action
It is the hexanicotinic acid ester of meso-inositol, also called inositol hexaniacinate (IHN) or inositol hexanicotinate or inositol nicotinate. Inositol Niacinate is a vasodilator and lipid-lowering agent. It improves circulation by releasing histamine, which causes the blood vessels to dilate and breaks up a protein needed for the clotting of blood. It also prevents the formation of lipids in the body, which helps to lower cholesterol and triglyceride levels.