Ipratropium Bromide Nasal prep
Indications
Ipratropium Bromide Nasal prep is used for:
Allergic rhinitis, Rhinorrhoea
Adult Dose
Nasal
Rhinorrhoea associated with rhinitis
Adult: As metered-dose nasal spray: 1-2 sprays into each nostril 2-3 times daily, up to 4 sprays into each nostril 3-4 times daily for up to 4 days when rhinorrhoea is associated w/ common cold or up to 3 wk when associated w/ seasonal allergic rhinitis.
Child Dose
Nasal
Rhinorrhoea associated with rhinitis
Child: As metered-dose nasal spray: >12 yr 1-2 sprays into each nostril 2-3 times daily.
Renal Dose
Administration
Contra Indications
Hypersensitivity
Precautions
Narrow-angle glaucoma or patients susceptible to glaucoma, Renal and hepatic impairment. Pregnancy, lactation, children, elderly.
Pregnancy-Lactation
Pregnancy Category: B
Lactation: Unknown whether distributed in breast milk
Interactions
Increased toxicity with other anticholinergic drugs.
Adverse Effects
Side effects of Ipratropium Bromide Nasal prep :
Acute angle-closure glaucoma, nasal dryness and epistaxis (nasal spray). Potentially Fatal: Anaphylactic reactions, atrial fibrillation, supraventricular tachycardia.
Mechanism of Action
Ipratropium bromide blocks the action of acetylcholine at parasympathetic sites in bronchial smooth muscle causing bronchodilation.