Iron (as Ferrous sulphate), Folic Acid

Indications

Iron (as Ferrous sulphate), Folic Acid is used for: Ferrous sulfate anhydrous
For the prevention and treatment of iron deficiency anemia [L2252].
Folic acid
Folic acid is indicated for the treatment of folic acid deficiency, megaloblastic anemia, and in anemias of nutritional origins, pregnancy, infancy, or childhood.

Adult Dose

Child Dose

Renal Dose

Administration

Contra Indications

Precautions

Pregnancy-Lactation

Interactions

Adverse Effects

Side effects of Iron (as Ferrous sulphate), Folic Acid :

Mechanism of Action

Ferrous sulfate anhydrous
Provides iron, an essential component in hemoglobin, myoglobin, and various enzymes [L2239]. Iron combines with porphyrin and globin chains to form hemoglobin, which is critical for oxygen delivery from the lungs to other tissues [L2263].
Folic acid
Folic acid, as it is biochemically inactive, is converted to tetrahydrofolic acid and methyltetrahydrofolate by dihydrofolate reductase (DHFR). These folic acid congeners are transported across cells by receptor-mediated endocytosis where they are needed to maintain normal erythropoiesis, synthesize purine and thymidylate nucleic acids, interconvert amino acids, methylate tRNA, and generate and use formate. Using vitamin B12 as a cofactor, folic acid can normalize high homocysteine levels by remethylation of homocysteine to methionine via methionine synthetase.